Results 71 to 80 of about 1,810 (157)

Additional file 1 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy

, 2023
Additional file 1: Genealogical trees of to the 6 consanguineous MMA probands.
Guey, Stéphanie, Hervé, Dominique, Kossorotoff, Manoëlle, Ha, Guillaume, Aloui, Chaker, Bergametti, Françoise, Arnould, Minh, Guenou, Hind, Hadjadj, Jessica, Dubois Teklali, Fanny, Riant, Florence, Balligand, Jean-Luc, Uzan, Georges, Villoutreix, Bruno O., Tournier-Lasserve, Elisabeth   +14 more
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Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]

, 2017
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC, Bina Joe, Biron P, Biron P, Bright R, Cook HW, Dublin LI, Dublin LI, Dupont J, Esunge PM, Felts JH, Garrod AE, Garrod AE, Garrod AE, Hamilton M, Hamilton M, Hamilton M, Joe B, Koffler M, Korner PI, Kuijpers MH, Lee YH, Lewis O, Markel’ AL, Matsukawa N, Mo R, Ohno Y, Pickering GW, Pravenec M, Sandosh Padmanabhan, Schlager G, Shear CL, Shiozawa M, Smolarek I, Zhang Y   +34 more
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MyGene2 automated match report: GUCY1A3

, 2017
MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If
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Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve [PDF]

, 2014
BACKGROUND: Bicuspid aortic valve (BAV) is the most common type of congenital heart disease with a population prevalence of 1-2%. While BAV is known to be highly heritable, mutations in single genes (such as GATA5 and NOTCH1) have been reported in few ...
David Newsom, Don Corsmeier, Elizabeth M Bonachea, Gloria Zender, Kim L McBride, Peter White, Sara Fitzgerald-Butt, Vidu Garg   +7 more
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Genetics of coronary artery disease – A clinician's perspective [PDF]

, 2014
Coronary artery disease (CAD) is the major cause of fatality and disability among all cardiovascular diseases (CVD). Intricate interactions of genes and environment dictate the outcomes of CAD.
Bailes, M., Barr, E. D., Bassa, C. G., Bhandari, S., Bhat, N. D. R., Burgay, M., Burke-Spolaor, S., Cameron, A. D., Champion, D. J., Eatough, R. P., Flynn, C. M. L., Freire, P. C. C., Jameson, A., Johnston, S., Karuppusamy, R., Keith, M. J., Kramer, M., Levin, L., Lorimer, D. R., Lyne, A. G., McLaughlin, M. A., Ng, C., Petroff, E., Possenti, A., Ridolfi, A., Stappers, B. W., Straten, W. van, Tauris, T. M., Tiburzi, C., Wex, N.   +29 more
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THE DOWNREGULATION OF GENES CONTROLLING VASCULAR TONE IN KIDNEYS OF ISIAH RATS WITH STRESS-INDUCED ARTERIAL HYPERTENSION

Вавиловский журнал генетики и селекции, 2015
The transcriptional activity of genes was studied in kidneys of hypertensive ISIAH and normotensive WAG rats in order to detect genes significantly expressed in kidneys of just one of the analyzed strains.
O. E. Redina, L. O. Klimov, N. I. Ershov, T. O. Abramova, L. N. Ivanova, L. A. Markel   +5 more
doaj  

Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. [PDF]

, 2017
Neurite initiation is the first step in neuronal development and occurs spontaneously in soft tissue environments. Although the mechanisms regulating the morphology of migratory cells on rigid substrates in cell culture are widely known, how soft ...
Chang, Ting-Ya, Chang, Ya-Chu, Chen, Chen, Cheng, Pei-Lin, Guo, Chin-Lin, Lee, Min, Lu, Chi-Huan, Lu, Shao-Tzu, Wang, Aijun, Wang, De-Yao   +9 more
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Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium [PDF]

, 2016
Background Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting.
Amouyel, P. (Philippe), Arveiler, D. (Dominique), Benjamin, E.J. (Emelia), Bis, J.C. (Joshua), Blankenberg, S. (Stefan), Boerwinkle, E.A. (Eric), Buckley, B.M. (Brendan M.), Carty, C. (Cara), Chasman, D.I. (Daniel I.), Cupples, L.A. (Adrienne), Dehghan, A. (Abbas), Demissie, S. (Serkalem), Ding, J. (Jingzhong), Ducimetiere, P. (P.), Dörr, M. (Marcus), Eiriksdottir, G. (Gudny), Evans, A. (Alun), Ferrieres, J. (Jean), Folsom, A.R. (Aaron R.), Ford, I., Franceschini, N. (Nora), Franco, O.H. (Oscar), Girman, C.J. (Cynthia J.), Gudnason, V. (Vilmundur), Harris, T.B. (Tamara), Heckbert, S.R. (Susan), Heiss, G. (Gerardo), Hofman, A. (Albert), Jensen, M.K. (Majken K.), Jukema, J.W. (Jan Wouter), Karvanen, J. (Juha), Kee, F. (Frank), Kraft, P. (Peter), Kritchevsky, S.B. (Stephen), Kuulasmaa, K. (Kari), Launer, L.J. (Lenore), Levy, D. (Daniel), Liu, Y. (YongMei), Lohman, K. (Kurt), Lumley, T. (Thomas), Markus, M.R.P. (Marcello R.P.), Morrison, A.C. (Alanna), O'Donnell, C.J. (Christopher J.), Psaty, B.M. (Bruce), Rice, K.M. (Kenneth), Ridker, P.M. (Paul M.), Rimm, E.B. (Eric B.), Rivadeneira Ramirez, F. (Fernando), Rose, L.M. (Lynda), Rotter, J.I. (Jerome I.), Salomaa, V. (Veikko), Silander, K. (Kaisa), Siscovick, D.S. (David), Smith, A.V. (Albert V.), Smith, N.L. (Nicholas), Stott, D.J. (David. J.), Taylor, K.D. (Kent), Trompet, S. (Stella), Uitterlinden, A.G. (André), Vasan, R.S. (Ramachandran S.), Virtamo, J. (Jarmo), Volzke, H. (Henry), Völker, U. (Uwe), Wagner, P.J. (Peter), Wang, Y.A. (Ying), White, C.C. (Charles), Wiklund, P.-G. (Per-Gunnar)   +66 more
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Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer [PDF]

, 2015
BACKGROUND Ovarian cancer is associated with poor long-term survival due to late diagnosis and development of chemoresistance. Tumour hypoxia is associated with many features of tumour aggressiveness including increased cellular proliferation ...
Blackshields, Gordon, Gallagher, Michael F., Martin, Cara M., McEvoy, Lynda M., O'Leary, John J., O'Toole, Sharon A., Sheils, Orla, Spillane, Cathy D., Stordal, Britta K.   +8 more
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mRNA-binding protein HuR in breast carcinogenesis [PDF]

, 2011
Breast cancer is the most common cancer among women. Although its prognosis has improved nowadays, methods to predict the progression of the disease or to treat it are not comprehensive.
Heinonen, Mira
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