Metabolic drift in the aging brain. [PDF]
, 2016 Brain function is highly dependent upon controlled energy metabolism whose loss heralds cognitive impairments. This is particularly notable in the aged individuals and in age-related neurodegenerative diseases.
Benton, H.P. +13 more
core +1 more source
Nurr1 protein is required for N-Methyl-d-aspartic Acid (NMDA) receptor-mediated neuronal survival [PDF]
, 2012 NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop.
Badiola Benito, Nahuai +6 more
core +2 more sources
Differential gene expression profile of retinoblastoma compared to normal retina. [PDF]
, 2010 PURPOSE: The retinoblastoma gene (RB1) is a tumor suppressor gene that was first discovered in a rare ocular pediatric tumor called retinoblastoma (RB).
Ganguly, Arupa, Shields, Carol L
core +1 more source
Genome-wide Association Study of Porcine Hematological Parameters in a Large White × Minzhu F2 Resource Population [PDF]
, 2012 Hematological traits, which are important indicators of immune function in animals, have been commonly examined as biomarkers of disease and disease severity in humans and animals.
Chen, Shaokang +14 more
core +2 more sources
Association of JAG1 gene polymorphism with systemic blood pressure in patients with obstructive sleep apnea: a prospective cohort study [PDF]
, 2019 Aim To assess the effects of single nucleotide polymorphisms (SNPs) on blood pressure control in patients with obstructive sleep apnea (OSA). Methods This prospective observational cohort study, conducted between 2004 and 2014, examined the associations ...
Ivan Tkáč +7 more
core +2 more sources
Specific dilation pattern in placental circulation and the NO/sGC role in preeclampsia placental vessels. [PDF]
Front Endocrinol (Lausanne), 2023 Tang J +8 more
europepmc +1 more source
PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle. [PDF]
Commun Biol, 2022 Hildebrand S +5 more
europepmc +1 more source
Double-layer omics analysis of castration- and X-ray-resistant prostate cancer cells. [PDF]
J Radiat Res, 2022 Iwanaga M +11 more
europepmc +1 more source
Kaposi’s sarcoma-associated herpesvirus replication and transcription activator regulates extracellular matrix signal pathway [PDF]
, 2016 Thesis (M.S.) University of Alaska Fairbanks, 2016Kaposi’s Sarcoma (KS) is a malignancy caused by infection with Kaposi’s Sarcoma-associated Herpesvirus [KSHV; also known as Human Herpesvirus 8 (HHV8)] in which tumor cells show a characteristic ‘spindle ...
Pfalmer, Daniel
core
Prioritization of risk genes for Alzheimer's disease: an analysis framework using spatial and temporal gene expression data in the human brain based on support vector machine. [PDF]
Front Genet, 2023 Wang S +5 more
europepmc +1 more source