Results 31 to 40 of about 76,053 (332)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Génesis del movimiento sindical y lucha armada. Historia del Movimiento 19 de abril en San Alberto, Cesar (1974-1990)

open access: yesHistoria Regional, 2023
El Movimiento 19 de abril fue una guerrilla colombiana que nació de una serie de contradicciones en los proyectos revolucionarios y el fraude electoral de 1970. Una de sus zonas de mayor influencia fue San Alberto, localizado en el departamento del Cesar
Diana Marcela Castellanos Bautista   +2 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The 1995 Attempted Derailing of the French TGV (High-Speed Train) and a Quantitative Analysis of 181 Rail Sabotage Attempts, MTI Report 09-12 [PDF]

open access: yes, 2010
On August 26, 1995, the Saturday of the final and busiest weekend of France’s summer holiday season, terrorists attempted to derail the TGV (Train à Grande Vitesse) between Lyon and Paris by planting a bomb.
Butterworth, Bruce R.   +2 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Indigenous beliefs and Zimbabwe’s War of Liberation: Inside the metaphysics

open access: yesThe Dyke, 2021
This paper recorded mysterious and miraculous events of the liberation war as expressed by those who were combatants on either side of the conflict during Zimbabwe’s liberation war.
Joshua Chakawa
doaj   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Naming the Combatants of the Colombian Armed Conflict in News Broadcasts: The Discursive Positioning of Journalists

open access: yesPalabra Clave, 2015
By examining the labels used to refer to the Colombian armed groups in news, this study analyses to what extent news incorporates the war communication of the armed groups.
Yeny Serrano
doaj  

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