Results 161 to 170 of about 1,187,762 (269)

A unified voice for evidence-based psychiatry: a global response to the WHO guidance on ECT. [PDF]

Eur Arch Psychiatry Clin Neurosci
Sartorius A, Zilles-Wegner D.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Systematic Review of International Guidelines for Addressing Alcohol Use Disorder in Pregnancy. [PDF]

Alcohol Clin Exp Res (Hoboken)
Cary CB, Hynes EOB, Terplan M, McNamara KA, Tardelli VS, Fidalgo TM, Bello JK, Doering M, Grucza RA, Jones HE, Duggal R, Kelly JC, Martins SS, Martin CE, Xu KY.   +14 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Improving protein-ligand complex generation with force field guidance. [PDF]

J Cheminform
Lai H, Wang T, Sirelkhatim H, Eaton J, Huang H, Rees B, Engkvist O, Janet JP, Wang X, Tibo A.   +9 more
europepmc   +1 more source

Echogenicity and the Echocardiographic Guidance

The Anatolian Journal of Cardiology, 2018
Balcı, Kevser Gülcihan, Balcı, Mustafa Mücahit   +1 more
openaire   +2 more sources

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source