Results 261 to 270 of about 5,911,359 (363)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

ESCP best practice: development, implementation and evaluation of sick day guidance in primary care in the Netherlands. [PDF]

Int J Clin Pharm
Coppes T, Koster ES, Philbert D, van Gelder T, Bouvy ML.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Beyond Computer-Aided Diagnosis: Artificial Intelligence as a "Digital Mentor" for POCUS Image Acquisition and Quality Assurance: A Narrative Review. [PDF]

Diagnostics (Basel)
Huh H, Park JJ.
europepmc   +1 more source

Guidance to educational settings about COVID-19: Updated 19 February 2020 [PDF]

, 2020

core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Patients' Perspectives on Antidepressant Discontinuation and the Pharmacists' Role. [PDF]

Basic Clin Pharmacol Toxicol
Bouarfa S, Göttgens W, Ligthart SA, Maarsingh OR, Kooij MJ, Bet PM, Hugtenburg JG.   +6 more
europepmc   +1 more source

Guidance for substance misuse education [PDF]

, 2012

core  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Cone-beam CT-derived parenchymal blood volume imaging in transarterial chemoembolization for hypovascular hepatic metastases: a case report. [PDF]

Front Oncol
Wang H, Liu X, Liu Y, Liu E, Lv B, Jiao Y, Zeng X, Gao B, Zhang H, Gao H, Chen G.   +10 more
europepmc   +1 more source