Results 21 to 30 of about 1,174,895 (219)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Aiken’s Index Analysis to Determine the Content Validity of the Self-Adjustment Instrument Based on Schneider’s Theory

Jurnal Ilmiah Bimbingan Konseling Undiksha
New students in Islamic boarding schools often face challenges in the process of adjusting due to environmental changes that include social, academic, and religious dimensions.
Rika Fitria, Muhammad Nur Wangid, Mami Hajaroh, Eva Imania   +3 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Exploring barriers to using modern contraceptives and accessing safe abortion care in women who terminated unintended pregnancies in Southern Ethiopia

BMC Women's Health
Background Unsafe abortion is a major medical and public health problem in Ethiopia and contributes significantly to abortion-related morbidity and mortality in the country.
Mahlet A. Woldetsadik, Yeshihareg Yoseph, Mekonnen Degu   +2 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Marriage Readiness among Final-Year University Students: The Role of Emotional Maturity and Interpersonal Communication Skills as Predictive Factors

Bisma The Journal of Counseling
Marriage readiness is an essential developmental task in early adulthood, yet many final-year students face the transition to marriage without adequate psychological and interpersonal preparedness.
Aprilia Setyowati, Diki Herdiansyah, Siti Muyana, Irvan Budhi Handaka, Corry Ardinana, Mufied Fauziah   +5 more
doaj   +1 more source

In situ airborne measurements of atmospheric parameters and airborne sea surface properties related to offshore wind parks in the German Bight during the project X-Wakes [PDF]

Earth System Science Data
Between 14 March 2020 and 11 September 2021, meteorological measurement flights were conducted above the German Bight in the framework of the project X-Wakes.
A. Lampert, R. Hankers, T. Feuerle, T. Rausch, M. Cremer, M. Angermann, M. Bitter, J. Füllgraf, H. Schulz, U. Bestmann, K. B. Bärfuss   +10 more
doaj   +1 more source

Navigating The Complexities of Parenting: The Interconnectedness of Forgiveness, Perfectionism, and Self-Compassion

International Journal of Positivity & Well-Being, 2023
The objective of this research was to examine the causal connections between parents' levels of perfectionism, forgiveness, cognitive distortions, and self-compassion.
Yağmur Çerkez, Simge Demir, Gizem Öneri Uzun   +2 more
doaj   +1 more source