Results 221 to 230 of about 105,034 (263)

It would be really great if I had greater confidence and ability there: Understanding the primary care physician experience with nutrition in training, clinical practice, and interprofessional collaboration. [PDF]

PLoS One
Hildebrand CA, Agrawal S, Albin J, Beck Dallaghan GL, Chen E, Gaviria D, Gilliland KO, Hilton A, Keyserling TC, Mayer-Davis E, Ammerman AS.   +10 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Reconsidering the spiritual-existential dimensions of perceived burden in advanced cancer. [PDF]

Palliat Support Care
Sa'idah I, Naqiyah N, Pratiwi TI, Purwoko B, Habsy BA, Annajih MZH, Fakhriyani DV.   +6 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation. [PDF]

J Med Internet Res
Mahlalela NB, Maboa O, Govathson C, Rossouw L, Long L, Greener R, Morris S, Cooper S, Frade S, Pascoe S, Chetty-Makkan C.   +10 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Parental Perspectives on Prenatal Counseling and Communication at the Time of Initial Evaluation and Diagnosis of Congenital Heart Disease. [PDF]

Am J Perinatol
Canella R, Paidas Teefey C, Christofferson J, McWhorter LG, Demianczyk AC, Kazak AE, Moldenhauer JS, Mitta M, Taboada C, Sood E.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Measuring Consistency Between Large Language Models' Responses to Preventive Care Queries and Official US Preventive Services Task Force (USPSTF) Recommendations: Systematic Test Involving All USPSTF Preventive Care Topics via Simulated User Prompts. [PDF]

JMIR AI
Johnson T, Gaissmaier W.
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source