Results 91 to 100 of about 3,059,962 (299)

Towards Robotic Companions: Understanding Handler-Guide Dog Interactions for Informed Guide Dog Robot Design [PDF]

open access: yesarXiv
Dog guides are favored by blind and low-vision (BLV) individuals for their ability to enhance independence and confidence by reducing safety concerns and increasing navigation efficiency compared to traditional mobility aids. However, only a relatively small proportion of BLV individuals work with dog guides due to their limited availability and ...
arxiv  

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Magnetic Vortex Guide [PDF]

open access: yesarXiv, 2015
A concept of magnetic vortex guide is proposed and numerically studied. Similar to the waveguides of electromagnetic waves, a magnetic vortex guide allows a vortex domain wall to move along a nanostrip without annihilation at the strip edges. It is shown by micromagnetic simulations that a magnetic nanostrip of a properly designed superlattice ...
arxiv  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Guided Reasoning: A Non-Technical Introduction [PDF]

open access: yesarXiv
We introduce the concept and a default implementation of Guided Reasoning. A multi-agent system is a Guided Reasoning system iff one agent (the guide) primarily interacts with other agents in order to improve reasoning quality. We describe Logikon's default implementation of Guided Reasoning in non-technical terms.
arxiv  

Monoidal Bousfield Localizations and Algebras over Operads: A User's Guide [PDF]

open access: yesEnchiridion: Mathematical User's Guides, Vol. 1 (2015), 2018
This paper is a companion for the paper "Monoidal Bousfield Localizations and Algebras over Operads," part of the author's PhD thesis. This paper was written in 2015 for the first edition of "Enchiridion: Mathematics User's Guides." More User's Guides can be found at https://mathusersguides.com/
arxiv  

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