Results 181 to 190 of about 9,297,024 (336)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Clinical efficacy of personalized 3D-printed modular navigation templates in assisting Femoral Neck System implantation for femoral neck fractures in young and middle-aged adults. [PDF]

BMC Musculoskelet Disord
Sheng X, Qian J, Zhu Y, Sha W, Tian S, Huang Y, Ge J.   +6 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Buyer's Guide: Buyer's Guide [PDF]

Environmental Science & Technology, 2002
  +6 more sources

Buyer's Guide: Buyer's Guide [PDF]

Environmental Science & Technology, 2001
  +6 more sources

Accuracy of Fully Guided Implant Placement Using Bone-Supported Stackable Surgical Guides in Completely Edentulous Patients-A Retrospective Study. [PDF]

J Clin Med
Bjelica R, Smojver I, Stojić L, Vuletić M, Katanec T, Gabrić D.   +5 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Uniformity Coefficient-Based Method for Improving the Wear Resistance of Mold Ejector Pin Guide Holes via Oblique Laser Shock Peening. [PDF]

Materials (Basel)
Liu E, Ye Y, Zhang Y, Mu S, Xu Z, Jiang W, Li Y.   +6 more
europepmc   +1 more source

Generating Visualizations Conversationally using Guided Autocomplete and LLMs [PDF]

Andrew Smith, Isaac M Neuhaus
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source