Results 41 to 50 of about 740,539 (229)

Endodontic Management of Dentinogenesis Imperfecta Using Guided Endodontics: A Case Report. [PDF]

Iran Endod J
Pulp canal calcification (PCC) is common in patients with dentinogenesis imperfecta (DGI). We present endodontic management of multiple anterior and posterior teeth with PCCs in a patient with DGI type II using guided endodontics.
Rahmatian M, Kazemi A, Dianat O, Safi Y.
europepmc   +2 more sources

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

Multidisciplinary Rehabilitation of Discoloured and Calcified Maxillary Incisors using MTA, EndoGuide-Assisted Canal Negotiation, and Aesthetic Restoration: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Managing calcified root canals and discoloured anterior teeth remains a clinical challenge due to diagnostic complexity and the risk of procedural complications.
Shwetana Kurundkar, Aditya Singh Patel, Manoj Chandak, Anuja Ikhar, Pratik Rathod   +4 more
doaj   +1 more source

Case reports in maxillary posterior teeth by guided endodontic access

, 2019
The localization of partial or completed root canal obliteration is a challenging task in endodontic practice. Recently, guided endodontics has become an alternative solution for those cases.
Vinicius de Carvalho Machado, Antônio Paulino Ribeiro Sobrinho, Gil Moreira Júnior, Lucas Moreira Maia, Nelson Renato França Alves da Silva, Manoel Brito Jr, Rodrigo Richard da Silveira   +6 more
core   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Sequential regenerative therapy using biologic‐based regeneration and connective tissue graft wall technique for a severe infrabony defect: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Regenerative therapy based on the principles of guided tissue regeneration (GTR) is an effective approach for the treatment of periodontal infrabony defects. However, complete resolution for deep and complex defects is not always predictable.
Wenwen Liu, Yilong Chen, Muhammad Saleh, Hom‐Lay Wang   +3 more
wiley   +1 more source

Antimicrobial and Antibiofilm Properties of Bioceramic Materials in Endodontics

, 2021
Microbes are prevalent in the root canals of necrotic teeth, and they are the cause of primary and post-treatment apical periodontitis. Bacteria can dwell within the infected root canal system as surface-adherent biofilm structures, which exhibit high ...
Haapasalo, M. (Markus), Zhejun Wang, Wang, Zhejun, Markus Haapasalo, Ya Shen, Shen, Ya   +5 more
core   +1 more source

Tooth autotransplantation combined with bone augmentation for reconstruction of the esthetic zone: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Reconstruction of cleft‐associated defects in the anterior maxilla is complicated by deficient hard and soft tissues, scarring, and altered anatomy. This case report describes tooth autotransplantation with simultaneous autogenous bone augmentation for replacement of a congenitally absent maxillary lateral incisor. Methods A 20‐year‐
Gurgen Khachatryan, Joseph Kan, Ekaterina Zernitckaia, Ulvi Shirnaliev   +3 more
wiley   +1 more source

Guided Endodontics [PDF]

, 2021
This final degree thesis is the result of a bibliographic search and synthesis carried out using databases such as Medline and Pubmed. The articles that have been selected on guided endodontics are from 2016 at the latest, taking into account the novelty
Bonturi , Clement Philippe Jules
core