Results 41 to 50 of about 70,896 (264)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Amplitude Dispersion Compensation for Damage Detection Using Ultrasonic Guided Waves
Sensors, 2016 Besides the phase and group velocities, the amplitude of guided wave mode is also frequency dependent. This amplitude dispersion also influences the performance of guided wave methods in nondestructive evaluation (NDE) and structural health monitoring ...
Liang Zeng +3 more
doaj +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Sensors, 2018 In this paper, a new approach to guided wave ray tomography for temperature-robust damage detection with time-of-flight (TOF) temperature compensation is developed.
Dan Li +5 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Signal Enhancement Technology Based on Ultrasonic Guided Wave Rail Bottom Crack Detection
Chengshi guidao jiaotong yanjiu［Objective］ During the propagation of guided waves in rails, there are problems of poor anti-interference ability and severe signal attenuation, which hinder the identification of rail bottom cracks.
HE Jiping +7 more
doaj +1 more source
Sensors, 2019 Quantitative and reliable monitoring of osseointegration will help further evaluate the integrity of the orthopaedic construct to promote novel prosthesis design and allow early mobilisation.
Benjamin Steven Vien +3 more
doaj +1 more source
Defects Inspection in Wires by Nonlinear Ultrasonic-Guided Wave Generated by Electromagnetic Sensors
Applied Sciences, 2020 Steel wires are widely used as raw materials for spring valves in engines. Considering the quality and safety issues of their structure, there is a demand to develop nondestructive inspection approaches to detect initial damages in steel.
Junpil Park +3 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source