Results 41 to 50 of about 670,059 (330)

Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.

Journal of Clinical Endocrinology and Metabolism, 2011
OBJECTIVE The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. PARTICIPANTS The Task Force was composed of a
Michael F. Holick, Neil C. Binkley, H.A. Bischoff-Ferrari, Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Murad, Connie M. Weaver   +7 more
semanticscholar   +1 more source

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.

Journal of Clinical Oncology, 2013
PURPOSE To update the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline recommendations for human epidermal growth factor receptor 2 (HER2) testing in breast cancer to improve the accuracy of HER2 testing and ...
Antonio C. Wolff, M. E. Hammond, David G. Hicks, M. Dowsett, Lisa M. McShane, Kimberly H. Allison, D. Allred, John M.S. Bartlett, M. Bilous, P. Fitzgibbons, W. Hanna, Robert B. Jenkins, P. Mangu, S. Paik, Edith A. Perez, Michael F. Press, Patricia A. Spears, Gail H. Vance, G. Viale, Daniel F. Hayes   +19 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Pilot Survey of Knowledge, Attitudes and Perceptions of Hajj Deployed Health Care Workers on Antibiotics and Antibiotic Prescriptions for Upper Respiratory Tract Infections: Results from Two Hajj Seasons

Tropical Medicine and Infectious Disease, 2020
Antimicrobial resistance (AMR) is a global public health issue. Upper respiratory tract infections (URTIs) are common illnesses during Hajj, for which antibiotics are often inappropriately prescribed.
Hamid Bokhary, Osamah Barasheed, Moataz Abd El Ghany, Ameneh Khatami, Grant A. Hill-Cawthorne, Harunor Rasheed, Hajj Research Team   +6 more
doaj   +1 more source

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.

Journal of Clinical Oncology, 2018
Purpose To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events in patients treated with immune checkpoint inhibitor (ICPi) therapy.
J. Brahmer, C. Lacchetti, B. Schneider, M. Atkins, Kelly J. Brassil, J. Caterino, I. Chau, M. Ernstoff, Jennifer M. Gardner, P. Ginex, S. Hallmeyer, Jennifer Holter Chakrabarty, N. Leighl, J. Mammen, D. McDermott, A. Naing, L. Nastoupil, T. Phillips, Laura D. Porter, I. Puzanov, C. Reichner, B. Santomasso, Carole Seigel, A. Spira, M. Suarez‐Almazor, Yinghong Wang, J. Weber, J. Wolchok, John A Thompson   +28 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

What Pediatricians Need to Know About the CDC Guideline on the Diagnosis and Management of mTBI

Frontiers in Pediatrics, 2018
Pediatric traumatic brain injury (TBI) is a growing health concern, with over half a million TBI-related emergency department (ED) visits annually. However, this is likely an underestimate of the true incidence, with many children presenting to their ...
Meeryo C. Choe, Andrew J. Gregory, Tamara M. Haegerich   +2 more
doaj   +1 more source

Causality Assessment Guidelines for Adverse Events Following Immunization with a Focus on Guillain–Barré Syndrome

Vaccines, 2020
South Korea operates a National Vaccine Injury Compensation Program (VICP) for people who experience adverse events following immunization (AEFI). To run this program rationally, it is a prerequisite to confirm whether adverse events were caused by ...
Hankil Lee, Hye-Young Kang, Sunghwa Cho, Seonyoung Park, Ah-Young Kim, Sun-Young Jung, Baik Lin Seong, Young-Mock Lee   +7 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Evidence-based practice guideline for the treatment of adult patients with depressive disorders. Part II: Psychotherapy

Psychiatria i Psychologia Kliniczna, 2018
This document is the second instalment in a two-part series outlining evidence-based recommendations for the treatment of adult patients with depressive disorders.
Vitaliy Voytenko, Krista Anderson, Nicole Wyngarden, Daniel Post, Eric Achtyes, Stephen Thomas, Evonne Edwards, Radosveta Stoyanov, Louis Nykamp, Selina Hill Lee   +9 more
doaj   +1 more source