Results 201 to 210 of about 232,235 (246)

A Retrospective Assessment of Guideline Adherence and Treatment Outcomes From Clostridioides difficile Infection Following the IDSA 2021 Clinical Guideline Update: Clostridioides difficile Infection. [PDF]

Open Forum Infect Dis
Dubberke ER, Li Q, Obi EN, Turzhitsky V, Siddiqui F, Nathanson BH.   +5 more
europepmc   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

A Retrospective Study Evaluating Guideline Adherence of Neonatal Parenteral Nutrition in a Belgian Neonatal Intensive Care Unit. [PDF]

Cureus
Nguyen TD, Meers G, Cortoos PJ, Steurbaut S, Cools F.   +4 more
europepmc   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Barriers to Optimal Clinician Guideline Adherence in Management of Markedly Elevated Blood Pressure: A Qualitative Study.

JAMA Netw Open
Lu Y, Arowojolu O, Qiu X, Liu Y, Curry LA, Krumholz HM.   +5 more
europepmc   +1 more source

Evaluating Antibiotic Treatment Guideline Adherence to Ongoing Antibiotic Stewardship in a Tertiary Care Setting: A Retrospective Observational Study. [PDF]

Can J Infect Dis Med Microbiol
Pant S, Corwin A, Adhikari P, Acharya SP, Acharya U, Silwal S, Dawadi P, Poudyal A, Paudyal V, Bhumiratana A.   +9 more
europepmc   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

Reducing Surgical Site Infections in Neurosurgery During the Intra-operative Phase: An Audit of National Institute for Health and Care Excellence (NICE) Guideline Adherence at a Major Trauma Centre. [PDF]

Cureus
Ahmed H, George KJ, Rasheed OW, Gilani A, Aldameiry MMM, Fayyaz M, Azeem A.   +6 more
europepmc   +1 more source

Polyaspartic Acid‐Calcium‐Lanthanum Complexes Induce Antibacterial Remineralization of Dentin and In‐Depth Occlusion of Dentinal Tubules

Advanced Science, EarlyView.
Polyaspartic acid‐calcium‐lanthanum (PAsp‐Ca‐La) complexes could induce antibacterial remineralization of demineralized dentin and in‐depth occlusion of dentinal tubules (DTs) with lanthanum‐doped hydroxyapatite (La‐HAp) via polyelectrolyte‐cation complexes pre‐precursor (PCCP) process, allowing the release of La3+ in response to acids generated by ...
Ling Zhu, Wei Liu, Yizhou Zhang, Zhifang Wu, Yiru Wang, Yuedan Xu, Haiyan Zheng, Hongli Zhang, Mengfei Yu, Xiaoting Jin, Zhe Wang, Zihuai Zhou, Baiping Fu   +12 more
wiley   +1 more source