Results 121 to 130 of about 16,189,469 (293)

IDB Newsletter: Vol. 8, no. 2, April 1970

open access: yes, 1970
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

IDB Newsletter: Vol. 7, no. 4, October 1969

open access: yes, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

IDB Newsletter: Vol. 7, no. 1, January 1969

open access: yes, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

PENGEMBANGAN PANDUAN PELATIHAN EFIKASI DIRI DALAM HUBUNGAN PERTEMANAN MELALUI STRATEGI EXPERIENTIAL LEARNING BAGI SISWA SMP

open access: yesJurnal Kajian Bimbingan dan Konseling, 2016
: The research aims to develop self-efficacy training guides in friendship through experiential learning strategies for junior high school students, so that the counselor can use it as a media of social guidance services for the student especially to ...
Layli Novita, Nur Hidayah
doaj  

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

open access: yesFEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller   +3 more
wiley   +1 more source

IDB News: Vol. 1, no. 6, July 1974

open access: yes, 1974
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Challenging Inequalities: Our Early Childhood Development Sector Framework Document at a Glance

open access: yes
Investing in the first five years of life is essential for early childhood development (ECD) and contributes to increasing societal productivity, reducing poverty, and promoting equality.
Inter-American Development Bank
core   +1 more source

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