Results 21 to 30 of about 2,708,416 (288)

Highlighting the need for de-implementation – Choosing Wisely recommendations based on clinical practice guidelines

open access: yesBMC Health Services Research, 2019
Background The Choosing Wisely campaign has spread to many countries. Methods for developing recommendations are inconsistent. We describe our process of developing such recommendations from a comprehensive national set of clinical practice guidelines ...
Raija Sipilä   +2 more
doaj   +1 more source

Outcomes after peritoneal dialysis catheter placement by laparoscopic surgery versus open surgery: systematic review and meta-analysis

open access: yesRenal Replacement Therapy, 2019
Success in peritoneal dialysis (PD) requires a well-functioning catheter, and catheter placement at PD initiation is extremely important for long-term PD.
Tsutomu Sakurada   +9 more
doaj   +1 more source

Comparison of peritoneal dialysis and hemodialysis as first renal replacement therapy in patients with end-stage renal disease and diabetes: a systematic review

open access: yesRenal Replacement Therapy, 2019
Background Diabetes has become the most common cause of end-stage renal disease (ESRD) requiring renal replacement therapy (RRT) in most countries around the world.
Yukio Maruyama   +9 more
doaj   +1 more source

More Guidelines than states: variations in U.S. lead screening and management guidance and impacts on shareable CDS development

open access: yesBMC Public Health, 2020
Background Pediatric lead exposure in the United States (U.S.) remains a preventable public health crisis. Shareable electronic clinical decision support (CDS) could improve lead screening and management. However, discrepancies between federal, state and
Jeremy J. Michel   +2 more
doaj   +1 more source

The close interaction between hypoxia-related proteins and metastasis in pancarcinomas

open access: yesScientific Reports, 2022
Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia.
Andrés López-Cortés   +17 more
doaj   +1 more source

Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes mellitus

open access: yesTrials, 2020
Background It is increasingly accepted that insufficient attention has been given to the patient health outcomes that are important to measure in comparative effectiveness research that will inform decision-making.
Susanna Dodd   +5 more
doaj   +1 more source

Ivermectin treatment for Strongyloides infection in patients with COVID-19

open access: yesCanada Communicable Disease Report, 2021
Ivermectin, an antiparasitic agent, is not recommended for prophylaxis or treatment of coronavirus disease 2019 (COVID-19). Inappropriate use of ivermectin for treatment of COVID-19 may make it less available for patients with serious parasitic ...
Elizabeth Leung   +12 more
doaj   +1 more source

Traitement à l’ivermectine pour l’infection à Strongyloides chez les patients atteints de COVID-19

open access: yesCanada Communicable Disease Report, 2021
L’ivermectine, un agent antiparasitaire, n’est pas recommandé pour la prophylaxie ou le traitement de la maladie à coronavirus 2019 (COVID-19).
Elizabeth Leung   +12 more
doaj   +1 more source

Molecular Pathogenesis and New Therapeutic Dimensions for Spinal Muscular Atrophy

open access: yesBiology, 2022
The condition known as 5q spinal muscular atrophy (SMA) is a devastating autosomal recessive neuromuscular disease caused by a deficiency of the ubiquitous protein survival of motor neuron (SMN), which is encoded by the SMN1 and SMN2 genes.
Andrés López-Cortés   +2 more
doaj   +1 more source

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