Time Mating Guinea Pigs by Monitoring Changes to the Vaginal Membrane throughout the Estrus Cycle and with Ultrasound Confirmation [PDF]
Methods and Protocols, 2021 One of the greatest challenges to the development and implementation of pregnancy therapeutics is the ability to rigorously test treatments in clinically relevant animal models.
Rebecca L. Wilson +4 more
doaj +3 more sources
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]
Journal of Experimental Medicine, 1994 Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD +8 more
core +2 more sources
Journal of Physiology, 2018 Over 30 years ago Professor David Barker first proposed the theory that events in early life could explain an individual's risk of non‐communicable disease in later life: the developmental origins of health and disease (DOHaD) hypothesis.
K J Botting +2 more
exaly +2 more sources
A comparative analysis of the intestinal metagenomes present in guinea pigs (
BMC Genomics, 2012 Background Guinea pig (Cavia porcellus) is an important model for human intestinal research. We have characterized the faecal microbiota of 60 guinea pigs using Illumina shotgun metagenomics, and used this data to compile a gene catalogue of its ...
Hildebrand Falk +12 more
doaj +5 more sources
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea [PDF]
Journal of Translational Medicine, 2010 Background Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss.
Haddad Luciana A +6 more
doaj +4 more sources
Finite element analysis on the human and guinea pig cochlear vibration patterns under bone conduction stimulations [PDF]
Scientific ReportsTo compare the vibrational patterns of human and guinea pig cochleae accurately, we developed and validated a novel finite element model of the guinea pig, leveraging it to analyze vibrational patterns in the cochlea.
Mingduo Zhao, Stefan Stenfelt
doaj +2 more sources
Establishment and optimization of an in vitro guinea pig oocyte maturation system. [PDF]
PLoS ONE, 2023 Guinea pigs are a valuable animal model for studying various diseases, including reproductive diseases. However, techniques for generating embryos via embryo engineering in guinea pigs are limited; for instance, in vitro maturation (IVM) technique is ...
Minhua Yao +10 more
doaj +2 more sources
Guinea pig model for evaluating the potential public health risk of swine and avian influenza viruses. [PDF]
PLoS ONE, 2010 BACKGROUND: The influenza viruses circulating in animals sporadically transmit to humans and pose pandemic threats. Animal models to evaluate the potential public health risk potential of these viruses are needed.
Yipeng Sun +12 more
doaj +2 more sources
THE PHYSIOLOGY OF THE IMMEDIATE REACTION OF ANAPHYLAXIS IN THE GUINEA-PIG [PDF]
Journal of Experimental Medicine, 1910 1. By an immediate anaphylactic reaction we mean the chain of symptoms which occur in highly sensitized guinea-pigs shortly after an intravenous or intracardiac injection of the toxic dose and usually end in death. 2.
John Auer, Paul A. Lewis
openalex +2 more sources
Conductance Changes of Na+ Channels during the Late Na+ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes [PDF]
Pharmaceuticals, 2023 Late sodium current (INa,late) is an important inward current contributing to the plateau phase of the action potential (AP) in the mammalian heart. Although INa,late is considered as a possible target for antiarrhythmic agents, several aspects of this ...
Balázs Horváth +8 more
doaj +3 more sources