Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. [PDF]
, 2013 The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of structurally diverse chemicals.
Bonati, Laura +10 more
core +3 more sources
Cloning and characterization of the hamster and guinea pig nicotinic acid receptors
Journal of Lipid Research, 2007 In this study, we present the identification and characterization of hamster and guinea pig nicotinic acid receptors. The hamster receptor shares ∼80–90% identity with the nucleotide and amino acid sequences of human, mouse, and rat receptors. The guinea
April Smith Torhan +3 more
doaj +1 more source
Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs. [PDF]
PLoS ONE, 2014 Guinea pigs have been used as a second animal model to validate putative anti-chlamydial vaccine candidates tested in mice. However, the lack of guinea pig-specific reagents has limited the utility of this animal model in Chlamydia sp.
Shradha Wali +12 more
doaj +1 more source
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]
, 1994 Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD +8 more
core +1 more source
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
Journal of Translational Medicine, 2010 Background Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss.
Haddad Luciana A +6 more
doaj +1 more source
Activation of relaxin family receptor 1 from different mammalian species by relaxin peptide and small-molecule agonist ML290 [PDF]
, 2015 Relaxin peptide (RLN), which signals through the relaxin family peptide 1 (RXFP1) GPCR receptor, has shown therapeutic effects in an acute heart failure clinical trial.
Alexander I Agoulnik +12 more
core +3 more sources
Perubahan Tinggi Sel Epitelium Villi Jejunum Marmut ( Cavia porcellus L.) Setelah Pemberian Teh Hijau [PDF]
, 2015 The research of the Guniea Pig Jejunum Villi Epithelium Cell Height After Given With Green Tea is aimed to know the effect of green tea on ventriculus villi epithelium cell height of female guinea pig.
Muliani, Hirawati
core +2 more sources
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action [PDF]
, 2014 A series of dibasic des-hydroxy β2 receptor agonists has been prepared and evaluated for potential as inhaled ultra-long acting bronchodilators. Determination of activities at the human β-adrenoreceptors demonstrated a series of highly potent and ...
Alcaraz L. +26 more
core +2 more sources
The multidrug resistance 1 gene Abcb1 in brain and placenta: comparative analysis in human and guinea pig. [PDF]
PLoS ONE, 2014 The Multidrug Resistance 1 (MDR1; alternatively ABCB1) gene product P-glycoprotein (P-gp), an ATP binding cassette transporter, extrudes multiple endogenous and exogenous substrates from the cell, playing an important role in normal physiology and ...
Jane J Pappas +7 more
doaj +1 more source