Disease Models & Mechanisms, 2017 Type 2 diabetes is a leading cause of morbidity and mortality among noncommunicable diseases, and additional animal models that more closely replicate the pathogenesis of human type 2 diabetes are needed.
Brendan K. Podell +5 more
semanticscholar +1 more source
Inhibitory effect of guinea pig serum on JTC-11 cell growth in vitro [PDF]
, 1967 The growth of JTC-11 cell line which was established from Ehrlich ascites carcinoma in vitro was inhibited by the addition of 2 per cent guinea pig serum to the control medium composed of 10 per cent bovine serum, 0.4 per cent lactalbumin hydrolysate and
Chikata, Eiji +5 more
core +1 more source
Biotechnology & Biotechnological Equipment, 2016 Domestic guinea pig is a model animal for human disease research. Uridine diphosphate glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) is an important human disease-related gene. In this study, the complete coding sequence of domestic guinea pig
Yang Deming, An Qingcong, Liu Yonggang
doaj +1 more source
5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release [PDF]
, 2014 The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT(3)) receptors ...
Aapro +54 more
core +3 more sources
Tibial osteosynthesis in a guinea pig (Cavia porcellus)
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015 A guinea pig was presented with left pelvic limb lameness after unknown trauma. Radiographs revealed complete oblique diaphyseal fracture of the distal third of the left tibia and fibula.
A.S. Macedo +7 more
doaj +1 more source
Cloning and characterization of the hamster and guinea pig nicotinic acid receptors
Journal of Lipid Research, 2007 In this study, we present the identification and characterization of hamster and guinea pig nicotinic acid receptors. The hamster receptor shares ∼80–90% identity with the nucleotide and amino acid sequences of human, mouse, and rat receptors. The guinea
April Smith Torhan +3 more
doaj +1 more source
Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs. [PDF]
PLoS ONE, 2014 Guinea pigs have been used as a second animal model to validate putative anti-chlamydial vaccine candidates tested in mice. However, the lack of guinea pig-specific reagents has limited the utility of this animal model in Chlamydia sp.
Shradha Wali +12 more
doaj +1 more source
THE PHYSIOLOGY OF THE IMMEDIATE REACTION OF ANAPHYLAXIS IN THE GUINEA-PIG
Journal of Experimental Medicine, 1910 1. By an immediate anaphylactic reaction we mean the chain of symptoms which occur in highly sensitized guinea-pigs shortly after an intravenous or intracardiac injection of the toxic dose and usually end in death. 2.
J. Auer, P. Lewis
semanticscholar +1 more source
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
Journal of Translational Medicine, 2010 Background Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss.
Haddad Luciana A +6 more
doaj +1 more source
Perubahan Tinggi Sel Epitelium Villi Jejunum Marmut ( Cavia porcellus L.) Setelah Pemberian Teh Hijau [PDF]
, 2015 The research of the Guniea Pig Jejunum Villi Epithelium Cell Height After Given With Green Tea is aimed to know the effect of green tea on ventriculus villi epithelium cell height of female guinea pig.
Muliani, Hirawati
core +2 more sources