The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination [PDF]
Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day.
A Alemu +103 more
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Guinea worm: from Robert Leiper to eradication. [PDF]
Guinea worm disease, dracunculiasis or dracontiasis, is an ancient disease with records going back over 4500 years, but until the beginning of the 20th century, little was known about its life cycle, particularly how humans became infected.
Cairncross, Sandy +2 more
core +2 more sources
Introduction: The global Guinea Worm Eradication Program has reduced numbers of human infections of Guinea worm disease (dracunculiasis) to 49 cases in four countries.
Christopher A. Cleveland +6 more
doaj +1 more source
One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo +135 more
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Screening strategies for a sustainable endpoint for Gambiense sleeping sickness [PDF]
Background. Gambiense human African trypanosomiasis (gHAT, sleeping sickness) is a vector-borne disease typically fatal without treatment. Intensified, mainly medical-based, interventions in endemic areas have reduced the occurrence of gHAT to ...
Aliee, Maryam +5 more
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Ghana is Free from the Guinea Worm after a 33-Year Eradication Program [PDF]
For several generations, people from some parts of Ghana have suffered in the hands of a yard-long "spaghetti-thin" worm, known as Dracunculus medinensis, which infects humans and leads to a disease known as Dracunculiasis, literally meaning "afflictions
Langbong Bimi +2 more
doaj
Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M +9 more
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The invertebrate Caenorhabditis elegans biosynthesizes ascorbate. [PDF]
l-Ascorbate, commonly known as vitamin C, serves as an antioxidant and cofactor essential for many biological processes. Distinct ascorbate biosynthetic pathways have been established for animals and plants, but little is known about the presence or ...
Adler, Lital N +5 more
core +2 more sources
Modeling the Effects of Spatial Heterogeneity and Seasonality on Guinea Worm Disease Transmission
Guinea worm disease is one of the neglected tropical diseases that is on the verge of elimination. Currently the disease is endemic in four countries, namely, Ethiopia, Mali, Chad, and South Sudan. Prior studies have demonstrated that climate factors and
Anthony A. E. Losio, Steady Mushayabasa
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Guinea worm eradication: Progress and challenges- should we beware of the dog? [PDF]
David Molyneux, Dieudonné P Sankara
doaj +2 more sources

