Results 211 to 220 of about 36,942 (288)

Homeobox B13 activates the hypoxia‐inducible factor 1 pathway through histone lactylation thereby reprogramming lipid metabolism and promoting sorafenib resistance in hepatocellular carcinoma

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Lactylation‐mediated metabolism reprogramming in HCC sorafenib resistance. In sorafenib‐resistant hepatocellular carcinoma (HCC) cells, lactate accumulation drives histone H3 lysine 18 lactylation (H3K18la). This modification is specifically enriched in the promoter region of homeobox B13 (HOXB13), activating HOXB13 transcription and upregulating its ...
Qingqing Xie   +5 more
wiley   +1 more source

Vitamin D receptor signaling in inflammatory senescence–associated skin aging: Mechanisms and therapeutic potentials

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan   +8 more
wiley   +1 more source

Clinical and Pathological Characteristics and Prognosis of Breast Cancer During Pregnancy and Postpartum: A Multicenter Retrospective Study

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Purpose The prognostic impact of the interval between the most recent childbirth and breast cancer diagnosis remains insufficiently defined, particularly when breast cancer diagnosed during pregnancy (PrBC) is distinguished from postpartum breast cancer (PPBC).
Liying Wang   +5 more
wiley   +1 more source

Ensemble Modeling Reveals Threats to Pollination Services From Asynchronous Range Shifts Between Camellia oleifera and Its Specialized Wild Bee Pollinators

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
This study employed ensemble species distribution models (SSDMs) to project the potential distributions of C. oleifera and these two key pollinators under current and future climate scenarios. We integrated field survey data with open biodiversity database records to simulate suitable habitats and quantify their spatiotemporal overlap.
Linjie Chen   +6 more
wiley   +1 more source

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