Results 181 to 190 of about 13,253 (266)

Computational Intelligence Accelerates CRISPR‐Cas‐Based Diagnostic Design

iLABMED, EarlyView.
Computational intelligence, including pangenome‐guided target mining, machine‐learning‐based guide RNA optimization, and autonomous AI agents, is shifting CRISPR diagnostic design from empirical screening to systematic, data‐driven engineering and accelerating the path from pathogen discovery to deployable diagnostics.
Hengyu Wang, Qiurun He, Xuhu Mao, Yong Sheng   +3 more
wiley   +1 more source

Morphometric and taxonomic approach to describe Heterospio variabilis (Annelida, Longosomatidae), a new species with three size-dependent morphotypes, from the Gulf of California, Eastern Pacific. [PDF]

PeerJ
Hernández-Alcántara P, Solis-Weiss V.
europepmc   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

iLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang, Jia Liu, Chengrong Bian, Wenwen Yuan, Wang Zhang, Fan Feng, Boan Li   +6 more
wiley   +1 more source

Fisheries management tools to support coastal and marine spatial planning: A case study from the Northern Gulf of California, Mexico. [PDF]

MethodsX, 2020
Morzaria-Luna HN, Turk-Boyer P, Hernández JMD, Polanco-Mizquez E, Downton-Hoffmann C, Cruz-Piñón G, Carrillo-Lammens T, Loaiza-Villanueva R, Valdivia-Jiménez P, Sánchez-Cruz A, Peña-Mendoza V, López-Ortiz AM, Koch V, Vázquez-Vera L, Arreola-Lizárraga JA, Amador-Castro IG, Suárez Castillo AN, Munguia-Vega A.   +17 more
europepmc   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Caligusselenecola sp. nov. (Siphonostomatoida, Caligidae) parasitic on the hairfin lookdown Selenebrevoortii (Gill) from the Gulf of California, Mexico, with some comments on Caritustolii Rangnekar, 1984. [PDF]

Zookeys
Morales-Serna FN, Yáñez-Rivera B, Gómez S.   +2 more
europepmc   +1 more source

Reduced fish diversity despite increased fish biomass in a Gulf of California Marine Protected Area. [PDF]

PeerJ, 2020
Ramírez-Ortiz G, Reyes-Bonilla H, Balart EF, Olivier D, Huato-Soberanis L, Micheli F, Edgar GJ.   +6 more
europepmc   +1 more source

Turning Water to Wine: An Analysis of Texas Wine Industry Water Management

Irrigation and Drainage, EarlyView.
ABSTRACT The Texas wine industry is expanding in scale and reputation during a period when sustainability concerns are increasingly visible and valuable to grape growers and wine producers in Texas. Most vineyard hectarage in Texas is in the High Plains and Hill Country American Viticultural Areas (AVAs), which rely on regional aquifers for water. With
Brock Burford, Colleen C. Myles, Justin Scheiner, Michael Cook   +3 more
wiley   +1 more source

‘Felt sense of anomaly’‐type transdiagnostic dissociative experiences in adolescents: Endorsed phenomenology and plausible mechanisms

JCPP Advances, EarlyView.
Abstract Background Research indicates dissociative experiences (DE) are prevalent in adolescents. However, the exact phenomenology and underlying mechanisms of dissociation in adolescence have yet to be clarified. The current study explores the presentation of, and possible psychological factors maintaining, dissociation in this population.
Emma Černis, Milan Antonović, Katie Lofthouse, Lottie Shipp, Polly Waite   +4 more
wiley   +1 more source