Results 11 to 20 of about 86,666 (204)

Computational modeling-directed combination treatment with etanercept and mifepristone mitigates neuroinflammation in a mouse model of Gulf War Illness. [PDF]

PLoS ONE
Gulf War Illness is a chronic multi-symptom disorder experienced by over 30% of veterans from the 1990-1991 Gulf War and is increasingly recognized to be driven by underlying persistent neuroinflammation resulting from chemical and physiological ...
Kimberly A Kelly, Christopher M Felton, Brenda K Billig, Ali A Yilmaz, James P O'Callaghan, Travis J A Craddock, Gordon Broderick, Nancy Klimas, Lindsay T Michalovicz   +8 more
doaj   +2 more sources

Epigenetic study of the long-term effects of gulf War illness [PDF]

Frontiers in Genetics
IntroductionGulf War Illness is a chronic multisymptomatic disorder that affects as many as 25-35% of the military personnel who were sent to the Persian Gulf war in 1991.
B. C. Jones, J. P. O’Callaghan, D. G. Ashbrook, L. Lu, P. Prins, W. Zhao, K. Mozhui   +6 more
doaj   +2 more sources

Treatment and life goals among veterans with Gulf War illness. [PDF]

PLoS ONE, 2023
Medically unexplained syndromes (MUS), also termed persistent physical symptoms, are both prevalent and disabling. Yet treatments for MUS are marked by high rates of patient dissatisfaction, as well as disagreement between patients and providers on the ...
Nicole Sullivan, Hannah Schorpp, Sarah Crosky, Scott Thien, Drew A Helmer, David R Litke, Wilfred R Pigeon, Karen S Quigley, Lisa M McAndrew   +8 more
doaj   +2 more sources

Gulf war illness: a tale of two genomes [PDF]

BMC Research Notes
Introduction Gulf War illness (GWI) is an environmentally-triggered chronic multisymptom illness typified by protean symptoms, in which mitochondrial impairment is evident. It has been likened to accelerated aging. Nuclear genetics of detoxification have
Beatrice A. Golomb, Richard I. Kelley, Jun Hee Han, Bruce Miller, Leeann Bui   +4 more
doaj   +2 more sources

Epigenetic analysis in a murine genetic model of Gulf War illness [PDF]

Frontiers in Toxicology, 2023
Of the nearly 1 million military personnel who participated in the 1990–1991 Gulf War, between 25% and 35% became ill with what now is referred to as Gulf War Illness (GWI) by the Department of Defense.
Khyobeni Mozhui, Khyobeni Mozhui, James P. O’Callaghan, David G. Ashbrook, Pjotr Prins, Wenyuan Zhao, Lu Lu, Byron C. Jones, Byron C. Jones   +8 more
doaj   +2 more sources

Bioenergetic impairment in Gulf War illness assessed via 31P-MRS [PDF]

Scientific Reports
Time for post-exercise phosphocreatine-recovery (PCr-R), deemed a robust index of mitochondrial function in vivo, was previously reported to be elevated (signifying impaired ATP production) in veterans with Gulf War illness (GWI).
Beatrice Alexandra Golomb, Jun Hee Han, Alexander Fung, Brinton Keith Berg, Bruce J. Miller, Gavin Hamilton   +5 more
doaj   +2 more sources

Central Executive Dysfunction and Deferred Prefrontal Processing in Veterans with Gulf War Illness. [PDF]

, 2013
Gulf War Illness is associated with toxic exposure to cholinergic disruptive chemicals. The cholinergic system has been shown to mediate the central executive of working memory (WM).
Bennett, Ilana J, Brigante, Ryan M, Haley, Robert W, Hubbard, Nicholas A, Hutchison, Joanna L, Motes, Michael A, Rypma, Bart, Shokri-Kojori, Ehsan   +7 more
core   +2 more sources

Oligodendrocyte involvement in Gulf War Illness [PDF]

Glia, 2019
AbstractLow level sarin nerve gas and other anti‐cholinesterase agents have been implicated in Gulf War illness (GWI), a chronic multi‐symptom disorder characterized by cognitive, pain and fatigue symptoms that continues to afflict roughly 32% of veterans from the 1990–1991 Gulf War.
Jillian Belgrad, Dipankar J. Dutta, Samantha Bromley‐Coolidge, Kimberly A. Kelly, Lindsay T. Michalovicz, Kimberly A. Sullivan, James P. O'Callaghan, Richard. Douglas Fields   +7 more
openaire   +2 more sources

Association of Atherosclerotic Cardiovascular Disease, Hypertension, Diabetes, and Hyperlipidemia With Gulf War Illness Among Gulf War Veterans

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Approximately 30% of the 700 000 Gulf War veterans report a chronic symptom‐based illness of varying severity referred to as Gulf War illness (GWI).
Sarah T. Ahmed, Ruosha Li, Peter Richardson, Saurendro Ghosh, Lea Steele, Donna L. White, Alice Nono Djotsa, Kellie Sims, Elizabeth Gifford, Elizabeth R. Hauser, Salim S. Virani, Robert Morgan, George Delclos, Drew A. Helmer   +13 more
doaj   +1 more source

The Effectiveness of Individualized Acupuncture Protocols in the Treatment of Gulf War Illness: A Pragmatic Randomized Clinical Trial. [PDF]

PLoS ONE, 2016
BACKGROUND:Gulf War Illness is a Complex Medical Illness characterized by multiple symptoms, including fatigue, sleep and mood disturbances, cognitive dysfunction, and musculoskeletal pain affecting veterans of the first Gulf War.
Lisa Conboy, Travis Gerke, Kai-Yin Hsu, Meredith St John, Marc Goldstein, Rosa Schnyer   +5 more
doaj   +1 more source