Results 141 to 150 of about 2,342,108 (381)
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Thiamine Acquisition Strategies Impact Metabolism and Competition in the Gut Microbe Bacteroides thetaiotaomicron. [PDF]
Thiamine (vitamin B1) is an essential cofactor for all organisms. Humans primarily acquire thiamine through their diet, and thiamine deficiencies have adverse neurological effects.
Costliow, Zachary A, Degnan, Patrick H
core
The Flavour Puzzle from an Orbifold GUT Perspective [PDF]
Wilfried Buchmüller
openalex +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Gauge Coupling Unification in Heterotic String Models with Gauge Mediated SUSY Breaking
We calculate the weak scale MSSM spectrum starting from a heterotic string theory compactified on an anisotropic orbifold. Supersymmetry breaking is mediated by vector-like exotics that arise naturally in heterotic string theories.
Anandakrishnan, Archana, Raby, Stuart
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Fregego krytyka dowodu ontologicznego (FREGE'S CRITICISM OF THE ONTOLOGICAL ARGUMENT) [PDF]
The paper reconstructs Frege's criticism of the ontological argument for the existence of God on the basis of various remarks scattered in his writings.
Arkadiusz Gut
doaj
F-Theory GUT Vacua on Compact Calabi-Yau Fourfolds
We present compact three-generation F-theory GUT models meeting in particular the constraints of D3-tadpole cancellation and D-term supersymmetry. To this end we explicitly construct elliptically fibered Calabi-Yau fourfolds as complete intersections in ...
A Collinucci +54 more
core +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Zagadnienie wolności osoby ludzkiej w ujęciu Leibniza (THE PROBLEM OF HUMAN FREEDOM ACCORDING TO LEIBNIZ) [PDF]
The article concerns the fundamental metaphysical problem of human freedom as it is discussed in Leibniz's philosophy. The essence of it can be expressed as follows: in what way the determinism developed by Leibniz goes along with his doctrine of human ...
Przemysław Gut
doaj

