Results 151 to 160 of about 2,005,973 (405)

Exophobic Quasi-Realistic Heterotic String Vacua [PDF]

open access: yes, 2009
We demonstrate the existence of heterotic-string vacua that are free of massless exotic fields. The need to break the non-Abelian GUT symmetries in k=1 heterotic-string models by Wilson lines, while preserving the GUT embedding of the weak-hypercharge ...
Acharya   +55 more
core   +1 more source

Genericity of Cosmic Strings Formation in SUSY GUTs [PDF]

open access: yesarXiv, 2004
The idea of GUT implies that the universe went through a series of phase transitions during which topological defects are expected to form. We investigate here the genericity of cosmic strings formation in realistic SUSY GUTs models. We conclude that all acceptable symmetry breaking schemes produce cosmic strings after the last inflationary phase ...
arxiv  

Flat directions in susy guts [PDF]

open access: yes, 2001
It is shown that a realistic SUSY SU(6) GUT can dynamically generate the GUT scale and solve at the same time the doublet-triplet splitting problem. The cosmological implications of such a model are briefly reviewed.
arxiv   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

open access: yesFEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He   +5 more
wiley   +1 more source

Genomic characterization and antimicrobial susceptibility of bovine intrauterine Escherichia coli and its relationship with postpartum uterine infections

open access: yesJournal of Integrative Agriculture, 2016
To investigate the roles of Escherichia coli in the pathogenesis of postpartum uterine diseases in dairy cows, a total of 145 E. coli isolates were recovered from 18 healthy cows (61 isolates) and 25 cows with clinical endometritis (84 isolates) at 25–35
Li-ming YANG   +5 more
doaj  

Mechanistic Insights Into the Cross-Feeding of Ruminococcus gnavus and Ruminococcus bromii on Host and Dietary Carbohydrates

open access: yesFrontiers in Microbiology, 2018
Dietary and host glycans shape the composition of the human gut microbiota with keystone carbohydrate-degrading species playing a critical role in maintaining the structure and function of gut microbial communities.
Emmanuelle H. Crost   +5 more
doaj   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Overweight and obesity are associated with colorectal neoplasia in an Australian outpatient population

open access: yesScientific Reports
Colorectal cancer is a major cause of cancer-related deaths within the Australian population. Colonoscopy and polypectomy represent effective forms of prevention.
Rina Kumar   +7 more
doaj   +1 more source

Approaches in studying the pharmacology of Chinese Medicine formulas: bottom-up, top-down—and meeting in the middle

open access: yesChinese Medicine, 2018
Investigating the pharmacology is key to the modernization of Chinese Medicine (CM) formulas. However, identifying which are the active compound(s) of CM formulas, which biological entities they target, and through which signaling pathway(s) they act to ...
Tao Huang   +10 more
doaj   +1 more source

Discrimination of Supersymmetric Grand Unified Models in Gaugino Mediation

open access: yes, 2011
We consider supersymmetric grand unified theory (GUT) with the gaugino mediated supersymmetry breaking and investigate a possibility to discriminate different GUT models in terms of predicted sparticle mass spectra.
Okada, Nobuchika, Tran, Hieu Minh
core   +1 more source

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