A novel MBOdCN S‐scheme heterojunction photocatalyst is fabricated using pristine Mg‐Bi2O3 and grayish g‐C3N4, where dynamic dual charge migration paths occur to accelerate exciton dissociation. This composite catalyst realizes high degradation efficiency of up to 99.56% of oxytetracycline (OTC) removal under optimized conditions. The material exhibits
Potlako J. Mafa+11 more
wiley +1 more source
Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap+10 more
wiley +1 more source
The gut microbiota shapes intestinal immune responses during health and disease
J. Round, S. Mazmanian
semanticscholar +1 more source
Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone
Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe+6 more
wiley +1 more source
Multi-Omics Analysis of Gut Microbiome and Host Metabolism in Different Populations of Chinese Alligators (<i>alligator sinensis</i>) During Various Reintroduction Phases. [PDF]
Wang C+8 more
europepmc +1 more source
Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang+7 more
wiley +1 more source
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome. [PDF]
Zhang Y+9 more
europepmc +1 more source
On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley +1 more source