This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu+38 more
wiley +1 more source
Research Status and Trends of Gut Microbiota and Intestinal Diseases Based on Bibliometrics. [PDF]
Sun X, Zhai J.
europepmc +1 more source
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source
Evaluation of extended-spectrum <i>β</i>-lactamase producing bacteria in feces of shelter dogs as a biomarker for altered gut microbial taxa and functional profiles. [PDF]
Abdi R, Datta S, Zawar A, Kafle P.
europepmc +1 more source
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen+16 more
wiley +1 more source
Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets. [PDF]
Oami T+5 more
europepmc +1 more source
The Chinese gut virus catalogue reveals gut virome diversity and disease-related viral signatures. [PDF]
Yan Q+21 more
europepmc +1 more source
Multiple primary malignancies and gut microbiome. [PDF]
Wu Y+8 more
europepmc +1 more source
How gut microbes affect Parkinson's disease: an editorial. [PDF]
Nasir R+6 more
europepmc +1 more source