Results 211 to 220 of about 114,048 (309)

Enzymatic carbon-fluorine bond cleavage by human gut microbes. [PDF]

Proc Natl Acad Sci U S A
Probst SI, Felder FD, Poltorak V, Mewalal R, Blaby IK, Robinson SL.   +5 more
europepmc   +1 more source

Beyond Canonical CO Oxidation: Structural and Evolutionary Insights Into a Non‐Canonical Carbon Monoxide Dehydrogenase

Angewandte Chemie, EarlyView.
Clade B carbon monoxide dehydrogenases (CODHs) remain enigmatic, diverging from canonical CODHs in structure and function. Here, we present the first characterization of Ruminococcus flavefaciens CODH (RfCODH), revealing occluded substrate pathways and attenuated CO oxidation activity.
Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land   +6 more
wiley   +2 more sources

How gut microbes affect Parkinson's disease: an editorial. [PDF]

Ann Med Surg (Lond)
Nasir R, Haseeb A, Saqlain Mustafa M, Mussarat A, Ali L, Ashir Shafique M, Abbasher Hussien Mohamed Ahmed K.   +6 more
europepmc   +1 more source

Microbes in the inflamed gut

This thesis investigates the gut microbiome's role in inflammatory bowel disease (IBD). The research emphasizes the importance of a multifactorial understanding of IBD that includes microbiome interactions, immune responses, and patient metabolism. Part I focuses on the microbiome in pediatric patients with Crohn's disease and ulcerative colitis. Multi-
openaire   +1 more source

Assessment of Genetic Correlations Between Tobacco or Alcohol Use and Neurodegenerative Diseases Using East Asian Genetic Ancestry Genome‐Wide Association Study Results

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent late‐onset neurodegenerative diseases worldwide. Both are influenced in part by genetic factors and are currently incurable. Tobacco and alcohol, the two most common substances used among the general adult population, are potential AD/PD risk factors and are also ...
Linda Wang, Wiame Belbellaj, Frida Lona‐Durazo, Sarah A. Gagliano Taliun   +3 more
wiley   +1 more source

Gut microbes-spinal connection is required for itch sensation. [PDF]

Gut Microbes
Jin T, Li SY, Zheng HL, Liu XD, Huang Y, Ma G, Zhao YX, Zhao XT, Yang L, Wang QH, Wang HJ, Gu C, Pan Z, Lin F.   +13 more
europepmc   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Reactivity of Autologous Serum IgG to Gut Microbes in Pediatric Ulcerative Colitis. [PDF]

Int J Mol Sci
Tabassum N, Nakayama-Imaohji H, Munyeshyaka E, Tada A, Kondo T, Kondo S, Kusaka T, Kuwahara T.   +7 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source