Results 291 to 300 of about 746,471 (377)

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren   +16 more
wiley   +1 more source

Pharmacomicrobiomics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich   +11 more
wiley   +1 more source

Structure, function, and quantitative biology of the Drosophila gut microbiome. [PDF]

open access: yesCurr Opin Microbiol
Ludington WB   +4 more
europepmc   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia   +4 more
wiley   +1 more source

Randomized Open-Label Pilot Study of the Influence of Probiotics and the Gut Microbiome on Toxic Metal Levels in Tanzanian Pregnant Women and School Children

open access: gold, 2014
Jordan E. Bisanz   +6 more
openalex   +1 more source

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