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Current Biology, 2022
All animals, from cnidarians to humans, are colonized with microbes, and the greatest diversity and magnitude of these host-associated microorganisms resides within the intestine. Referred to as the gut microbiome, membership can be as simple as one species of bacteria or can be composed of hundreds to thousands of different microbes across the domains
Gavin A, Kuziel, Seth, Rakoff-Nahoum
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All animals, from cnidarians to humans, are colonized with microbes, and the greatest diversity and magnitude of these host-associated microorganisms resides within the intestine. Referred to as the gut microbiome, membership can be as simple as one species of bacteria or can be composed of hundreds to thousands of different microbes across the domains
Gavin A, Kuziel, Seth, Rakoff-Nahoum
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The gut microbiome in epilepsy
Microbial Pathogenesis, 2020The close relationship between epilepsy and autoimmune diseases and the fact that the cause of epilepsy is idiopathic in 60% of cases suggest that intestinal microbiota may play a role in the etiology of epilepsy. In this study, we analyzed and compared the intestinal microbiota composition of patients with idiopathic focal epilepsy (n = 30) and ...
Bengü Altunan +3 more
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Inflammation & Allergy-Drug Targets, 2014
Since the discovery and use of the microscope in the 17(th) century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may ...
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Since the discovery and use of the microscope in the 17(th) century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may ...
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Nature Reviews Microbiology, 2014
Ley and colleagues show that human genetic variation influences the composition of the gut microbiota, which affects health.
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Ley and colleagues show that human genetic variation influences the composition of the gut microbiota, which affects health.
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The Gut Microbiome and Obesity
Current Oncology Reports, 2016The gut microbiome consists of trillions of bacteria which play an important role in human metabolism. Animal and human studies have implicated distortion of the normal microbial balance in obesity and metabolic syndrome. Bacteria causing weight gain are thought to induce the expression of genes related to lipid and carbohydrate metabolism thereby ...
Gerard E. Mullin, George Kunnackal John
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Vitamins for the Gut Microbiome
Trends in Molecular Medicine, 2020A main target in microbiome research is the understanding and ability to safely and effectively modulate the microbiome to improve health. Hereto, we discuss the role of vitamins in relation to the gut microbiome and present a rationale for the modulation of gut microbial communities via selected systemic and colon-targeted vitamin administration.
Yuan-Kun Lee +3 more
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Surgical Infections, 2023
Abstract The gut has been hypothesized to be the "motor" of multiple organ dysfunction in sepsis. Although there are multiple ways in which the gut can drive systemic inflammation, increasing evidence suggests that the intestinal microbiome plays a more substantial role than previously appreciated. An English language literature review was performed to
Nathan J, Klingensmith +1 more
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Abstract The gut has been hypothesized to be the "motor" of multiple organ dysfunction in sepsis. Although there are multiple ways in which the gut can drive systemic inflammation, increasing evidence suggests that the intestinal microbiome plays a more substantial role than previously appreciated. An English language literature review was performed to
Nathan J, Klingensmith +1 more
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Overview of the Gut Microbiome
Seminars in Neurology, 2023AbstractThe human gastrointestinal tract is home to trillions of microorganisms—collectively referred to as the gut microbiome—that maintain a symbiotic relationship with their host. This diverse community of microbes grows and changes as we do, with developmental, lifestyle, and environmental factors all shaping microbiome community structure ...
Lisa, Blackmer-Raynolds +1 more
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Fractures and the gut microbiome
Current Opinion in HIV and AIDS, 2018The role of the gut microbiome in the pathogenesis of several inflammatory, non-AIDS comorbidities, such as cardiovascular disease, cognitive impairment and liver disease has become a focus of recent research. Low bone mineral density (BMD) and increased fracture incidence in people living with HIV (PLWH) is also widely reported, however, the ...
Paddy Mallon +3 more
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The gut microbiome and hypertension
Nature Reviews Nephrology, 2023A large body of evidence has emerged in the past decade supporting a role for the gut microbiome in the regulation of blood pressure. The field has moved from association to causation in the last 5 years, with studies that have used germ-free animals, antibiotic treatments and direct supplementation with microbial metabolites.
Joanne A. O’Donnell +3 more
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