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Shaping the gut microbiome

Nature Reviews Microbiology, 2014
Ley and colleagues show that human genetic variation influences the composition of the gut microbiota, which affects health.
openaire   +5 more sources

The Gut Microbiome and Obesity

Current Oncology Reports, 2016
The gut microbiome consists of trillions of bacteria which play an important role in human metabolism. Animal and human studies have implicated distortion of the normal microbial balance in obesity and metabolic syndrome. Bacteria causing weight gain are thought to induce the expression of genes related to lipid and carbohydrate metabolism thereby ...
Gerard E. Mullin, George Kunnackal John
openaire   +3 more sources

Vitamins for the Gut Microbiome

Trends in Molecular Medicine, 2020
A main target in microbiome research is the understanding and ability to safely and effectively modulate the microbiome to improve health. Hereto, we discuss the role of vitamins in relation to the gut microbiome and present a rationale for the modulation of gut microbial communities via selected systemic and colon-targeted vitamin administration.
Yuan-Kun Lee   +3 more
openaire   +3 more sources

Gut Microbiome in Sepsis

Surgical Infections, 2023
Abstract The gut has been hypothesized to be the "motor" of multiple organ dysfunction in sepsis. Although there are multiple ways in which the gut can drive systemic inflammation, increasing evidence suggests that the intestinal microbiome plays a more substantial role than previously appreciated. An English language literature review was performed to
Nathan J, Klingensmith   +1 more
openaire   +2 more sources

Gut Microbiome and Antibiotics

Archives of Medical Research, 2017
Despite that the human gastrointestinal tract is the most populated ecological niche by bacteria in the human body, much is still unknown about its characteristics. This site is highly susceptible to the effects of many external factors that may affect in the quality and the quantity of the microbiome.
Victoria E. Ruiz   +3 more
openaire   +3 more sources

Overview of the Gut Microbiome

Seminars in Neurology, 2023
AbstractThe human gastrointestinal tract is home to trillions of microorganisms—collectively referred to as the gut microbiome—that maintain a symbiotic relationship with their host. This diverse community of microbes grows and changes as we do, with developmental, lifestyle, and environmental factors all shaping microbiome community structure ...
Lisa, Blackmer-Raynolds   +1 more
openaire   +2 more sources

What defines a healthy gut microbiome?

Gut
The understanding that changes in microbiome composition can influence chronic human diseases and the efficiency of therapies has driven efforts to develop microbiota-centred therapies such as first and next generation probiotics, prebiotics and ...
M. Van Hul   +5 more
semanticscholar   +1 more source

Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health

Gut, 2020
The human gut microbiome is a complex ecosystem, densely colonised by thousands of microbial species. It varies among individuals and depends on host genotype and environmental factors, such as diet and antibiotics.
M. Fassarella   +5 more
semanticscholar   +1 more source

The microbiome and gut homeostasis

Science, 2022
Changes in the composition of the gut microbiota are associated with many human diseases. So far, however, we have failed to define homeostasis or dysbiosis by the presence or absence of specific microbial species. The composition and function of the adult gut microbiota is governed by diet and host factors that regulate and direct microbial growth ...
Jee-Yon Lee   +2 more
openaire   +2 more sources

Fractures and the gut microbiome

Current Opinion in HIV and AIDS, 2018
The role of the gut microbiome in the pathogenesis of several inflammatory, non-AIDS comorbidities, such as cardiovascular disease, cognitive impairment and liver disease has become a focus of recent research. Low bone mineral density (BMD) and increased fracture incidence in people living with HIV (PLWH) is also widely reported, however, the ...
Paddy Mallon   +3 more
openaire   +3 more sources

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