Results 181 to 190 of about 693,536 (346)

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

Arthritis &Rheumatology, EarlyView.
Objective A pathogenetic role of CD8+ T lymphocytes in radiographic axial spondyloarthritis (r‐axSpA) and other spondyloarthritis (SpA) is sustained by genome‐wide association studies and by the expansion of public T cell clonotypes in the target tissues.
Giorgia Paldino, Valentina Tedeschi, Valentina Proganò, Erica Salvati, Valerio Licursi, Eleonora Vertecchi, Alexandru L. Bivolaru, Emanuele Molteni, Rossana Scrivo, Mattia Congia, Alberto Cauli, Rosalba Caccavale, Marino Paroli, Martina Kunkl, Loretta Tuosto, Rosa Sorrentino, Maria Teresa Fiorillo   +16 more
wiley   +1 more source

Gout and NLRP3 inflammasome biology

Arthritis &Rheumatology, Accepted Article.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilisation, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal‐induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health

, 2008
Volker Mai, Peter V. Draganov
openalex   +1 more source

Gut microbiota-derived extracellular vesicles form a distinct entity from gut microbiota. [PDF]

mSystems
Kaisanlahti A, Turunen J, Hekkala J, Mishra S, Karikka S, Amatya SB, Paalanne N, Kruger J, Portaankorva AM, Koivunen J, Jukkola A, Vihinen P, Auvinen P, Leppä S, Karihtala P, Koivukangas V, Hukkanen J, Vainio S, Samoylenko A, Bart G, Lahti L, Reunanen J, Tejesvi MV, Ruuska-Loewald T.   +23 more
europepmc   +1 more source

Gut microbiota

Shenshuaikang enema restores the microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-kB ...
openaire   +1 more source

Mucosal‐associated invariant T cells in rheumatic diseases.

Arthritis &Rheumatology, Accepted Article.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Impact of antibiotics on the gut microbiota of critically ill patients

, 2008
G. Iapichino, Maria Luisa Callegari, Silvia Marzorati, Marco Cigada, Davide Corbella, Susanna Ferrari, Lorenzo Morelli   +6 more
openalex   +1 more source

Gut Microbiota and Exercise: Probiotics to Modify the Composition and Roles of the Gut Microbiota in the Context of 3P Medicine. [PDF]

Microb Ecol
Liu Y, Hu Y, Ma B, Wang Z, Wei B.
europepmc   +1 more source

Advances in Small Molecule Inhibitors Targeting the Bacterial Lipoprotein Transport System (Lol) in Gram‐Negative Bacteria

Chemistry – An Asian Journal, EarlyView.
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley   +1 more source

Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota [PDF]

, 2010
Samah O. Noor, Karyn P. Ridgway, Louise Scovell, E. Kate Kemsley, Elizabeth K. Lund, Crawford P. Jamieson, Ian T. Johnson, Arjan Narbad   +7 more
openalex   +1 more source