Results 191 to 200 of about 932,371 (335)

Role of gut microbiota in type 2 diabetes pathophysiology

open access: yesEBioMedicine, 2020
M. Gurung   +6 more
semanticscholar   +1 more source

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

Gut microbiota, nutrients, and depression. [PDF]

open access: yesFront Nutr
Qiao Y   +8 more
europepmc   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

open access: yesAdvanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan   +5 more
wiley   +1 more source

Added sugars, gut microbiota, and host health. [PDF]

open access: yesGut Microbes
Zhang Y, Walker RW, Kaplan RC, Qi Q.
europepmc   +1 more source

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki   +9 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, EarlyView.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

Analysis of Gut Microbiota and Their Metabolites in CADASIL Patients. [PDF]

open access: yesJ Clin Neurol
Watanabe-Hosomi A   +8 more
europepmc   +1 more source

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