Results 201 to 210 of about 896,723 (386)

Half‐Pipe Melt Electrowritten Scaffolds Support Engineering of an Immunocompetent Hydrogel‐Embedded Intestine‐on‐a‐Chip

Advanced Science, EarlyView.
The immunocompetent Intestine‐on‐a‐Chip (IoC) is developed using melt electrowritten (MEW) half‐pipes. Intestinal epithelial cell (IEC) culture is optimized in the MEW‐based IoC, followed by co‐culture with monocyte‐derived dendritic cells (moDCs) and T cells in 3D hydrogels.
Robine Janssen, Henrike S. Schulze, Claire M. L. Nelissen, Marta G. Valverde, Andrei Hrynevich, Govardus A. H. de Jong, Anne Metje van Genderen, Jos Malda, Shanna Bastiaan‐Net, Linette E. M. Willemsen, Rosalinde Masereeuw   +10 more
wiley   +1 more source

Does a polyphagous caterpillar have the same gut microbiota when feeding on different species of food plants? [PDF]

, 2002
Ana Sittenfeld, Lorena Uribe‐Lorío, Marielos Mora, Vanesa Nielsen, Glen Arrieta, Daniel H. Janzen   +5 more
openalex  

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 [PDF]

, 2009
Kendle M. Maslowski, Angélica T. Vieira, Aylwin Ng, Jan Kranich, Frédéric Sierro, Di Yu, Heidi Schilter, Michael S. Rolph, Fabienne Mackay, David Artis, Ramnik J. Xavier, Mauro Martins Teixeira, Charles R. Mackay   +12 more
openalex   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

PROBIOTIC INTERVENTION IN THE NEONATAL PERIOD: LONG-TERM EFFECTS ON GUT MICROBIOTA

, 2005
Minna Rinne, M Kalliom ki, Seppo Salminen, Erika Isolauri   +3 more
openalex   +1 more source

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source

Insights into the Mechanisms of Immune‐Checkpoint Inhibitors Gained from Spatiotemporal Dynamics of the Tumor Microenvironment

Advanced Science, EarlyView.
This review summarizes recent advances in the spatiotemporal dynamics of the tumor microenvironment (TME). It highlights the roles of diverse immune and stromal cell populations, spatial architecture of the TME, as well as the gut and tumor microbiota in influencing responses to immune checkpoint inhibitors (ICIs), by integrating insights from single ...
Yuanyuan Zhang, Zhihua Liu
wiley   +1 more source

Pattern extraction of structural responses of gut microbiota to rotavirus infection via multivariate statistical analysis of clone library data [PDF]

, 2009
Meiling Zhang, Menghui Zhang, Chenhong Zhang, Huimin Du, Guifang Wei, Xiaoyan Pang, Haokui Zhou, Binbin Liu, Liping Zhao   +8 more
openalex   +1 more source

Role of gut microbiota in type 2 diabetes pathophysiology

EBioMedicine, 2020
M. Gurung, Zhipeng Li, H. You, R. Rodrigues, D. Jump, A. Morgun, N. Shulzhenko   +6 more
semanticscholar   +1 more source

Polyphenol‐Based Functional Materials: Structural Insights, Composite Strategies, and Biomedical Applications

Advanced Science, EarlyView.
This schematic representation illustrates the interaction mechanisms between polyphenolic compounds and various materials (metals, proteins, polysaccharides, alkaloids, etc.). And explains the potential clinical application value of these materials (nanoparticles, coatings, films, capsules, and hydrogels constructed using polyphenols) in the fields of ...
Songwen Xue, Wen Tan, Shuifang Mao, Haibo Pan, Xingqian Ye, Natthawuddhi Donlao, Jinhu Tian   +6 more
wiley   +1 more source