Results 321 to 330 of about 896,723 (386)

Altered Gut Microbiota and Endocannabinoid System Tone in Obese and Diabetic Leptin-Resistant Mice: Impact on Apelin Regulation in Adipose Tissue

, 2011
Lucie Geurts, Vladimir Lazarević, Muriel Derrien, Amandine Everard, Marie Van Roye, Claude Knauf, Philippe Valet, Myriam Girard, Giulio G. Muccioli, Patrice François, Willem M. de Vos, Jacques Schrenzel, Nathalie M. Delzenne, Patrice D. Cani   +13 more
openalex   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Physical Activity and Metabolic Disorders-What Does Gut Microbiota Have to Do with It? [PDF]

Curr Issues Mol Biol
Sokal-Dembowska A, Polak-Szczybyło E, Helma K, Musz P, Setlik M, Fic W, Wachowiak D, Jarmakiewicz-Czaja S.   +7 more
europepmc   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis. [PDF]

Front Pharmacol
Guo S, Zhao J, Zhu R, Fan Z, Liu S, Wu W.   +5 more
europepmc   +1 more source

Microbiome‐Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr, Shen Cheng, Mahmoud Al‐Kofahi, Christopher Staley, Pamala A. Jacobson   +4 more
wiley   +1 more source

Healthy Ageing and Gut Microbiota: A Study on Longevity in Adults. [PDF]

Microorganisms
Deng L, Xu J, Xue Q, Wei Y, Wang J.
europepmc   +1 more source

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

Clinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren, Jing An, Wei Chen, Jiao Li, Xing Li, Anning Yin, Jing Wang, Wei Wang, Jingyun Cheng, Jian Kang, Yaqing Xu, Yueyue Lu, Juan Su, Qian Zhou, Huipeng Wan, Zimeng Zhang, Ping An   +16 more
wiley   +1 more source

Gut Microbiota Metabolites Targeting the Immune Response in Sepsis: Mechanisms and Therapies. [PDF]

Int J Gen Med
Xu P.
europepmc   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

Barrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source