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Deconstructing the GWAS library: next-generation GWAS
Physiological ReviewsGenome-wide association studies (GWAS) have identified numerous common genetic variants associated with cardiovascular traits and diseases. These studies have increased our understanding of the genetic architecture of cardiac diseases and have facilitated the identification of genetic risk factors in patients.
Weirui Zhang +10 more
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2023
In this workshop on Genome-Wide Association Studies (GWAS), participants gained hands-on experience using PLINK software in a Unix command-line environment and RStudio for analyzing single nucleotide polymorphisms (SNPs) to identify genes associated with diseases or specific phenotypes.
Repušić, Doris, Pleić, Nikolina
openaire
In this workshop on Genome-Wide Association Studies (GWAS), participants gained hands-on experience using PLINK software in a Unix command-line environment and RStudio for analyzing single nucleotide polymorphisms (SNPs) to identify genes associated with diseases or specific phenotypes.
Repušić, Doris, Pleić, Nikolina
openaire
2019
Over the past decade, genome-wide association studies (GWAS) have evolved into a powerful tool to investigate genetic risk factors for human diseases via a hypothesis-free scan of the genome. The success of GWAS for psychiatric disorders and behavioral traits have been somewhat mixed, partly owing to the complexity and heterogeneity of these traits ...
Mehta, Divya, Czamara, Darina
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Over the past decade, genome-wide association studies (GWAS) have evolved into a powerful tool to investigate genetic risk factors for human diseases via a hypothesis-free scan of the genome. The success of GWAS for psychiatric disorders and behavioral traits have been somewhat mixed, partly owing to the complexity and heterogeneity of these traits ...
Mehta, Divya, Czamara, Darina
openaire +3 more sources
SECRET-GWAS: Confidential Computing for Population-Scale GWAS
AbstractGenomic data from a single institution lacks global diversity representation, especially for rare variants and diseases. Confidential computing can enable collaborative GWAS without compromising privacy or accuracy, however, due to limited secure memory space and performance overheads previous solutions fail to support widely used regression ...Jonah Rosenblum +2 more
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2013
The term post-GWAS analyses here refers to two somewhat distinct general topics; first are a compendium of analyses that are typically performed after one or more GWAS studies of a particular disease have been completed. These analyses include pooled or meta-analysis used in order to combine results of two or more studies, typically with the help of ...
openaire +1 more source
The term post-GWAS analyses here refers to two somewhat distinct general topics; first are a compendium of analyses that are typically performed after one or more GWAS studies of a particular disease have been completed. These analyses include pooled or meta-analysis used in order to combine results of two or more studies, typically with the help of ...
openaire +1 more source