Results 121 to 130 of about 106,280 (313)
Light‐Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression
Angewandte Chemie, EarlyView.A photo‐triggered CRISPR/Cas12a machinery for gene editing is introduced. The machinery is applied for endogenous DNA methyltransferase 1 (DNMT1) gene editing and for in vitro disruption of the hepatocyte growth factor (HGF) gene. The machinery is used for in vivo knockout and disruption of the HGF gene in HepG2 tumors, resulting in effective apoptosis
Hong Liu +7 more
wiley +2 more sources
The impact of surgical complications on health-related quality of life in women undergoing gynecologic and gynecologic oncology procedures: a prospective longitudinal cohort study [PDF]
, 2016 Kemi M. Doll +7 more
openalex +3 more sources
Associations between social risk factors and surgical site infections after colectomy and abdominal hysterectomy [PDF]
, 2019 Importance: Surgical site infection (SSI) is an important patient safety outcome. Although social risk factors have been linked to many adverse health outcomes, it is unknown whether such factors are associated with higher rates of SSI.
Barker, Abigail +5 more
core +1 more source
Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer [PDF]
, 2011 BACKGROUND: Ovarian cancer is the sixth most common cancer among women and the leading cause of death in women with gynaecological malignancies. Opinions differ regarding the role of ultra-radical (extensive) cytoreductive surgery in ovarian cancer ...
Ang, C +4 more
core +1 more source
Advanced Science, EarlyView.The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei +7 more
wiley +1 more source
Morbidity after surgical management of cervical cancer in low and middle income countries: A systematic review and meta-analysis [PDF]
, 2019 Objective: To investigate morbidity for patients after the primary surgical management of cervical cancer in low and middle-income countries (LMIC). Methods: The Pubmed, Cochrane, the Cochrane Central Register of Controlled Trials, Embase, LILACS and ...
Allanson, Emma R +6 more
core +1 more source
Real-time Surgical Tools Recognition in Total Knee Arthroplasty Using Deep Neural Networks [PDF]
arXiv, 2018 Total knee arthroplasty (TKA) is a commonly performed surgical procedure to mitigate knee pain and improve functions for people with knee arthritis. The procedure is complicated due to the different surgical tools used in the stages of surgery. The recognition of surgical tools in real-time can be a solution to simplify surgical procedures for the ...
arxiv
A Wearable In‐Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood
Advanced Science, EarlyView.MenstruAI integrates a paper‐based biosensor into sanitary pads to detect biomarkers in menstrual blood, enabling accessible, lab‐free diagnostics health. The platform supports early disease detection, especially in underserved communities, while challenging menstrual stigma and opening pathways for scalable, inclusive, and sustainable population ...
Lucas Dosnon +3 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study aimed to clarify the epidemiology of hemorrhoids by leveraging a comprehensive nationwide healthcare claims database in Japan. By analyzing invasive treatments for hemorrhoids over a 5‐year period (2018–2022), we identified key demographic patterns, including distinct bimodal peaks in incidence among males and females, and highlighted ...
Masamitsu Kido +8 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley +1 more source