Results 161 to 170 of about 497,572 (262)

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis, Johanna E. Vriezekolk, Frédérique H. C. Bollen, Dirk E. Schrander, Arnt F. A. Schellekens, Bart J. F. van den Bemt   +5 more
wiley   +1 more source

Retraction Note: Letrozole versus clomiphene citrate for superovulation in Egyptian women with unexplained infertility: a randomized controlled trial. [PDF]

Arch Gynecol Obstet
Ibrahim MI, Moustafa RA, Abdel-Azeem AA.
europepmc   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, EarlyView.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source

Consensus-based guideline of the Korean Society of Gynecologic Oncology for high-risk human papillomavirus testing in cervical cancer screening. [PDF]

Obstet Gynecol Sci
Kim JH, Shim SH, Min KJ, Lee JK, Yoo CW, Kwon MJ, Lee SW, Bae J.   +7 more
europepmc   +1 more source

Correction: Endometrial biopsy performed before the first in vitro fertilization does not impact the early pregnancy rate. [PDF]

Sci Rep
Cellier M, Werlen S, Mery L, Genod A, Felloni B, Semay T, Trombert B, Chauleur C, Raia-Barjat T.   +8 more
europepmc   +1 more source

Integration of 3D-printed simulation models into a PAG fellowship curriculum: impact on trainee confidence and curriculum acceptability. [PDF]

Front Med (Lausanne)
Dumont T, From A, Rosca NP, Posner G, Mitsakakis N, Hayawi L, O'Reilly H, Lobos AT, McLean L.   +8 more
europepmc   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source

Clinical practice guideline for high-risk human papillomavirus testing in cervical cancer screening: a consensus statement from the Korean Society of Gynecologic Oncology. [PDF]

J Gynecol Oncol
Kim JH, Shim SH, Min KJ, Lee JK, Yoo CW, Kwon MJ, Lee SW, Bae J.   +7 more
europepmc   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Laparoscopic uterine-preserving management of ruptured pyometra using open drainage: a case report. [PDF]

J Surg Case Rep
Hirano Y, Sato H, Yamaoka Y, Kiyose M, Takeuchi Y, Hamaguchi F, Ibuchi S, Takemura Y, Onishi Y, Takaishi Y, Kan S, Masuda M, Kawaharamura K, Ando Y, Taguchi N, Kakui K.   +15 more
europepmc   +1 more source