Results 191 to 200 of about 770,373 (401)
A study of the pulmonary complications of preterm infants after prenatal corticosteroids prophylaxis in a major Bulgarian hospital [PDF]
, 2019 : An increasingly common problem in obstetrics and neonatology is premature birth. This problem is the cause of many health complications in premature neonates and is leading to neonatal mortality.
Buttigieg, George G. +3 more
core
Advanced Science, EarlyView.COL1A1, a major component of ECM, contributes to chemoresistance and poor prognosis in ovarian cancer. Halofuginone (HF) attenuates CAF‐secreted COL1A1 through mTOR‐eIF2α‐ATF4 axis. Notably, HF disrupts collagen deposition to form the looser ECM and facilitates CD8+ T cell infiltration, partially via M2‐M1 macrophage polarization to enhance ...
Wenxin Li +8 more
wiley +1 more source
Advanced Science, EarlyView.A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang +14 more
wiley +1 more source
Rapid hyperspectral photothermal mid-infrared spectroscopic imaging from sparse data for gynecologic cancer tissue subtyping [PDF]
arXivOvarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several drawbacks: it is qualitative, time-intensive, and heavily dependent on the quality of staining. Mid-infrared (MIR)
arxiv
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, EarlyView.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
, 2022 Cancer Communications, Volume 42, Issue 12, Page 1407-1411, December 2022.
Chao Liu +9 more
wiley +1 more source
Cancer, Volume 129, Issue 2, Page 283-295, 15 January 2023., 2023 Abstract Background Antibody–drug conjugates (ADCs) have complex molecular structures and have been tested in numerous clinical trials. Therefore, understanding the mechanisms of their toxicity when applied in medical practice is of high importance. Methods In a systematic review and meta‐analysis of data gathered from different scientific databases ...
Youwen Zhu +3 more
wiley +1 more source
Advanced Science, EarlyView.This study employs the Tishchenko coupling reaction to obtain bio‐based bisphenols containing degradable ester bonds with 100% atom utilization. Based on these bio‐based bisphenols, a fully bio‐based polyurethane Covalent Adaptable Networks are constructed, while simultaneously endowing the material with closed‐loop recyclability, degradability, and ...
Jiewen Wang +7 more
wiley +1 more source