Results 241 to 250 of about 390,053 (266)

Should the age range of the Dutch hrHPV‐based cervical cancer screening program be broadened? A modelling study using cohort effects

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Cervical cancer incidence in the Netherlands is increasing among women in younger birth cohorts. This raises concerns about the start and end ages of the country's human papillomavirus (HPV) screening program, which currently includes women ages 30 to 60.
Sylvia Kaljouw   +3 more
wiley   +1 more source

Time to pathologic diagnosis of suspicious breast lesions: An institution‐based study in five Ethiopian hospitals

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The World Health Organization's Global Breast Cancer Initiative set the benchmark to diagnose breast cancer within 2 months of the first contact with a health care provider. This study analyzed the diagnostic journey of women with breast symptoms at five Ethiopian hospitals. Of the 345 women interviewed who received a diagnostic workup of a
Friedemann Rabe   +12 more
wiley   +1 more source

Nationwide implementation and evaluation of the Tumor‐First workflow for genetic testing in ovarian carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The Tumor‐First workflow is a genetic testing strategy developed to detect pathogenic variants in ovarian cancer risk genes. Recently implemented in the Netherlands, this workflow aims to stratify germline testing while providing information on the effectiveness of PARP inhibitor therapy.
Vera M. Witjes   +50 more
wiley   +1 more source

The TESTBREAST journey: Revisiting the importance of early detection by frequent screening of women at high risk of breast cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Women who are at high risk of breast cancer (BC), either because of a BRCA1/2 mutation or family history, require more aggressive screening. Here, the authors report on the clinical characteristics of the high‐risk women who developed BC during the TESTBREAST study. Of the 1108 participants, 124 (16.5%) developed breast cancer. Their median
Layla Andour   +40 more
wiley   +1 more source

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk   +5 more
wiley   +1 more source

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart   +26 more
wiley   +1 more source

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