Results 311 to 320 of about 791,631 (404)

Novel para‐phenylenediamine‐based derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An in vitro preliminary characterization

open access: yesChemMedChem, Accepted Article.
ROR1 kinase is an underexplored promising target for the development of novel anticancer drugs, being strongly expressed in several cancer cell lines, but poorly in non‐tumor cells. This property, together with the scarce number of molecules effective against ROR1, led us to design and develop a research program aimed to the discovery of new chemical ...
Gerardina Smaldone   +17 more
wiley   +1 more source

Benefits of Hormonal Contraception Across the Lifespan: A Case-Based, Interactive Curriculum. [PDF]

open access: yesMedEdPORTAL
Panakam A   +5 more
europepmc   +1 more source

QTc Interval Changes in Preeclampsia vs. Normal Pregnancy: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pregnancy induces significant adaptations in the cardio‐autonomic nervous system, with additional cardiac stress in preeclampsia potentially impacting ventricular repolarization. Despite the widespread use of QT‐prolonging drugs during pregnancy, the extent of heart rate (HR)‐corrected QT (QTc) interval changes during normal pregnancy and preeclampsia ...
Omar A. Aboshady   +4 more
wiley   +1 more source

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