Results 41 to 50 of about 683,972 (341)

Feasibility of palliating recurrent gynecological tumors with MRGHIFU: comparison of symptom, quality-of-life, and imaging response in intra and extra-pelvic disease

International Journal of Hyperthermia, 2021
Objective To document longitudinal symptom, quality-of-life and imaging response in patients with recurrent gynecological tumors treated with magnetic resonance guided high intensity focused ultrasound (MRgHIFU), and compare changes in patients with ...
Georgios Imseeh, Sharon L. Giles, Alexandra Taylor, Matthew R. D. Brown, Ian Rivens, Richard Gordon-Williams, Gail ter Haar, Nandita M. deSouza   +7 more
doaj   +1 more source

3D Printing and Its Current Status of Application in Obstetrics and Gynecological Diseases

Bioengineering, 2023
3D printing technology is a novel method of utilizing computer-generated three-dimensional models for drawing, assembling special bioinks, and manufacturing artificial organs and biomedical products.
Caihong Hu, Weishe Zhang, Ping Li
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

A novel and cost-effective model to screen and treat cervical cancer and precancers at the point of care

Frontiers in Public Health
BackgroundCervical cancer has a high incidence to high mortality rate and poses an important global burden that disproportionately affects women in underdeveloped areas of the world.
Jean M. Bouquet, Emily Morris, Isain Zapata, Isain Zapata   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Development and evaluation of a “simulator-based” ultrasound training program for university teaching in obstetrics and gynecology–the prospective GynSim study

Frontiers in Medicine
IntroductionThis study addresses the challenges of ultrasound education in obstetrics and gynecology, focusing on the potential benefits of simulation techniques in medical training.
Johannes Weimer, Florian Recker, Annette Hasenburg, Holger Buggenhagen, Karla Karbach, Lia Beer, Andreas Weimer, Lina Schiestl, Liv Lorenz, Roman Kloeckner, Anna Dionysopoulou   +10 more
doaj   +1 more source

A modified three-port “hidden scars” surgical approach in gynecology: A surgeon's experience of an initial 72 cases

Gynecology and Minimally Invasive Therapy, 2014
Objective: The study objectives were to determine the surgical outcomes of a personal series of gynecological patients treated with a modified three-port “hidden scars” surgical approach (HS surgical approach) for the treatment of benign gynecological ...
Felix Wu Shun Wong, Eric Tat Choi Lee
doaj   +1 more source

A Review of the Complex Relationship between Irritable Bowel Syndrome and Infertility

Medicina, 2020
Irritable bowel syndrome (IBS) is a gastrointestinal disease that negatively affects up to 20% of the population. Infertility is defined as a disorder of the reproductive system described by lack of success in achieving pregnancy after more than a year ...
Carmen Anton, Alin Ciobica, Bogdan Doroftei, Radu Maftei, Ciprian Ilea, Natalia Darii Plopa, Maria Bolota, Emil Anton   +7 more
doaj   +1 more source

A Novel Ensemble of Fourier Transform Infrared Spectroscopic Biosensing and Deep Learning Postprocessing for Diagnosis of Endometrial Cancer

Engineering Proceedings, 2023
Cancers are prevalent worldwide, affecting a substantial amount of the global population, while early and proactive diagnosis of the disease continues to be a global medical challenge.
Ejay Nsugbe, Dephney Mathebula, Dawn Adams   +2 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source