Results 41 to 50 of about 507,240 (308)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A novel and cost-effective model to screen and treat cervical cancer and precancers at the point of care

Frontiers in Public Health
BackgroundCervical cancer has a high incidence to high mortality rate and poses an important global burden that disproportionately affects women in underdeveloped areas of the world.
Jean M. Bouquet, Emily Morris, Isain Zapata, Isain Zapata   +3 more
doaj   +1 more source

GRADE Use in Evidence Syntheses Published in High-Impact-Factor Gynecology and Obstetrics Journals: A Methodological Survey

, 2023
Objective: To identify and describe the certainty of evidence of gynecology and obstetrics systematic reviews (SRs) using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
Yang, Hui-Juan, Li, Xin-Yu, He-Li Xu, Zhang, De-Yu, Shuang Zhang, Xin-Yu Li, Hao, Ying-Ying, Hui-Juan Yang, Ying-Ying Hao, Li, Yi-Zi, Wu, Qi-Jun, Zhang, Shuang, Gong, Ting-Ting, Yi-Zi Li, Qi-Jun Wu, De-Yu Zhang, Xu, He-Li, Ting-Ting Gong   +17 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Development and evaluation of a “simulator-based” ultrasound training program for university teaching in obstetrics and gynecology–the prospective GynSim study

Frontiers in Medicine
IntroductionThis study addresses the challenges of ultrasound education in obstetrics and gynecology, focusing on the potential benefits of simulation techniques in medical training.
Johannes Weimer, Florian Recker, Annette Hasenburg, Holger Buggenhagen, Karla Karbach, Lia Beer, Andreas Weimer, Lina Schiestl, Liv Lorenz, Roman Kloeckner, Anna Dionysopoulou   +10 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

A Complicated Case of Thrombotic Thrombocytopenic Purpura in Pregnancy with Superimposed Preeclampsia

Oman Medical Journal
A 32-year-old woman at 26 weeks gestation presented with severe unexplained thrombocytopenia with signs and symptoms of severe pregnancy-induced hypertension and what appeared to be hemolysis, elevated liver enzymes, and low platelet count syndrome ...
Ikram Abdelaziz Shinko, Zenab Yusuf Tambawala, Shabnam Saquib , Saba Al Sayari   +3 more
doaj   +1 more source

Patient involvement in research within the Gynecological Cancer InterGroup: A call to action for a systematic approach: Results from a survey

Health Science Reports, 2023
Background and Aims Involving patients in research, not only as trial subjects, is not a newly established practice. Over the last two decades, patient roles have gradually expanded to become active research contributors, creating a more patient‐centered
Ivana Nohová, John Andrews, Bénédicte Votan, Austin Miller, Jalid Sehouli, Regina Berger   +5 more
doaj   +1 more source

Obstetrics and Gynecology

, 1987
Hill provides a brief overview of the past year's developments in obstetrics and gynecology, concentrating on ethical issues in human reproduction. Among the topics mentioned are abortion, sex education for adolescents, artificial insemination by donor (
Hill, Edward C.
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source