Results 51 to 60 of about 379,262 (266)

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

The general analysis of animals brought to mustafa kemal university, faculty of veterinary medicine, clinic of obstetrics and gynecology department between the years 2010-2015 [PDF]

Eurasian Journal of Veterinary Sciences
Aim: In this research, it was aimed to analyze the animals which brought to the clinics of Mustafa Kemal University, Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology also the reasons of applications and the classification of the ...
Mustafa Kemal Sarıbay, Gökhan Doğruer, Yaşar Ergün, Ayşe Merve Köse, Ece Koldaş   +4 more
doaj  

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Specification for Ovarian Tissue Cryopreservation and Transplantation [PDF]

Zhongguo quanke yixue, 2023
Beijing Obstetrics and Gynecology Hospital，Capital Medical University, Committee of Fertility Protection and Preservation of China Association for the Promotion of Health Science and Technology
doaj   +1 more source

AI‐Assisted Ultrasensitive Biosensing using Metal‐Electrolyte‐Metal‐Insulator‐Silicon Structure Based on Oxygen‐Tunable Iridium Oxide Nanonets for Lysyl‐Oxidase‐Like‐2 Breast Cancer Detection

Advanced Electronic Materials, EarlyView.
An oxygen‐controlled iridium‐oxide (IrOx) nano‐net structure is developed to enhance the sensitivity of metal‐electrolyte‐metal‐insulator‐silicon (MEMIS) biosensors. Integrated with a deep learning model, this platform achieves a high accuracy of 94.8% for detecting the breast cancer biomarker LOXL2.
Chiao‐Fan Chiu, Pankaj Kumar, Long Nguyen Minh Le, Ping‐Hsuan Wu, Punnatorn Boonyoung, Shen Tingyang, Abhijit Aich, Yi‐Pin Chen, Shih‐Yin Huang, Siddheswar Maikap   +9 more
wiley   +1 more source

Epistemic Injustice in Obstetrics and Gynecology

Yixue yu zhexue
Epistemic injustice in the medical field is primarily manifested through the epistemic privilege of healthcare professionals, which leads to the underestimation of patients' epistemic credibility.
Sitian LIU
doaj   +1 more source

Temporal availability of obstetrics and gynecology clinics in Taiwan: A nationwide survey

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: Obstetrician–gynecologists are the main providers of women's healthcare. However, workforce shortages and excessive workloads among these providers have been encountered in many countries.
Wei-Ting Chang, Hsin-I Leu, Huang-Pin Chen, Ming-Hwai Lin, Tzeng-Ji Chen, Shinn-Jang Hwang, Li-Fang Chou, Peng-Hui Wang   +7 more
doaj   +1 more source

Proteomics in obstetrics and gynecology

Indian Journal of Human Genetics, 2011
Proteomics helps to understand the basic biological processes critical to normal cellular functions as well as the development of diseases. It identifies the essential components of these processes and exploits these components as targets in the development of new methods to prevent or treat diseases.
Lekhwani, Seema, Shankar, Vijay, Vaswani, N.D.   +2 more
openaire   +3 more sources

Clinical Implementation and Perioperative Outcomes of Robot‐Assisted Pelvic Exenteration for Primary Rectal Cancer: A Multicenter Japanese Experience

Annals of Gastroenterological Surgery, EarlyView.
Robot‐assisted pelvic exenteration (RPE) was performed with acceptable perioperative outcomes in selected patients with primary rectal cancer. It may serve as a complementary approach at institutions with sufficient experience in PE, whereas open surgery remains essential for extensive or technically demanding disease.
Shoma Yamamoto, Hiroyasu Kagawa, Yusuke Yatabe, Yusuke Kinugasa   +3 more
wiley   +1 more source