Results 41 to 50 of about 14,208 (205)

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]

, 1996
Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Blethen, Sandra L., Geissler, Wayne M., Mendonca, Berenice B., Schwarz, Hans P., Russell, David D., Bloise, Walter, Grumbach, Melvin M., Davis, Daphne L., Andersson, Stefan, New, Maria I., Wu, Ling, Witchel, Selma F., Griffin, James E., Cutler Jr., Gordon B., Wilson, Jean D.   +14 more
core   +1 more source

Gynecomastia in a Patient Taking Meloxicam—A Case Report

Journal of Primary Care & Community Health, 2020
Gynecomastia is benign enlargement of glandular tissue in the male breast. It occurs due to an imbalance of estrogen and testosterone. It may be unilateral or bilateral.
Steven L. Rosas, Mark E. Deyo-Svendsen, Rachel Z. Oldfather, Michael R. Phillips, T. Andrew Israel, Emily R. Weisenbeck   +5 more
doaj   +1 more source

Clinical and genetic features of pediatric hereditary polyposis syndromes in Israel: A nationwide multicenter cohort

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hereditary polyposis syndromes in children are rare, heterogeneous disorders associated with significant morbidity and long‐term risk of malignancy. Current data on their presentation, management, and outcomes in pediatric populations remain limited.
Shlomi Cohen, Tal Cozacov, Ilana Weintraub, Ron Shaoul, Oren Ledder, Dotan Yogev, Mordechai Slae, Ranya Egbarieh, Galina Ling, Anat Yerushalmy‐Feler   +9 more
wiley   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Accidental gynecomastia in children [PDF]

, 2001
peer reviewedAny palpable breast tissue in men is abnormal except during: the neonatal period, adolescence and in elderly age. Gynecomastia in prepubertal children may be due to enhanced endogenous oestrogen production, drugs or unknown causes. After the
Toppari, J., Thonneau, P., Myers, P., Kulin, H., Russo, G., Huff, J., Chiumello, G., Joffe, M., Bourguignon, Jean-Pierre, De Muinck Keizer-Schrama, S., Sgaramella, P., Stroppa, L., Andersson, A.-M., Guarneri, M. P., Daxenberger, A.   +14 more
core   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Randomized Controlled Study of Tamoxifen in the Treatment of Gynecomastia in Male Patients with Liver Cirrhosis [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim:Gynecomastia is a complication in patients with liver cirrhosis. Tamoxifen has shown promise in managing gynecomastia in puberty.
Abdelrazek Alahwal, Asem Elfert, Walaa Elkhalawany, Reham Elkhouly   +3 more
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Gynecomastia

, 2020
Gynecomastia is a swelling of the male breast as a result of the growth of two components: The adipose and the glandular tissue, sometimes unilateral, but more often occurring in bilateral form.
Tripoli M., Massimiliano Tripoli, Cordova A., Adriana Cordova   +3 more
core   +1 more source