Results 71 to 80 of about 331,967 (351)

Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults [PDF]

, 2006
Among younger adults, the ability to willfully regulate negative affect, enabling effective responses to stressful experiences, engages regions of prefrontal cortex (PFC) and the amygdala.
Alexander, Andrew L., Davidson, Richard J., Frye, Corrina J., Greischar, Lawrence L., Jackson, Cory A., Johnstone, Tom, Kalin, Ned H., Schaefer, Hillary S., Thurow, Marchell E., Urry, Heather L., Van Reekum, Carina Marije   +10 more
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Differences in Intrinsic Brain Abnormalities Between Patients With Left- and Right-Sided Long-Term Hearing Impairment

Frontiers in Neuroscience, 2019
Unilateral hearing impairment is characterized by asymmetric hearing input, which causes bilateral unbalanced auditory afferents and tinnitus of varying degrees. Long-term hearing imbalance can cause functional reorganization in the brain.
Xiaoxiao Xie, Yongbo Liu, Xiaowei Han, Xiaowei Han, Pei Liu, Hui Qiu, Junfeng Li, Huachen Yu   +7 more
doaj   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]

, 1997
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad, Barbacid, Mariano, Frisén, Jonás, Río Fernández, José Antonio del, Silos-Santiago, Inmaculada, Soriano García, Eduardo   +5 more
core   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Multimodal magnetic resonance imaging study of treatment-naïve adults with attention-deficit/hyperactivity disorder. [PDF]

PLoS ONE, 2014
BACKGROUND: Attention-Deficit/Hiperactivity Disorder (ADHD) is a prevalent disorder, but its neuroanatomical circuitry is still relatively understudied, especially in the adult population.
Tiffany M Chaim, Tianhao Zhang, Marcus V Zanetti, Maria Aparecida da Silva, Mário R Louzã, Jimit Doshi, Mauricio H Serpa, Fabio L S Duran, Sheila C Caetano, Christos Davatzikos, Geraldo F Busatto   +10 more
doaj   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Neural Basis of Depression Related to a Dominant Right Hemisphere: A Resting-State fMRI Study

Behavioural Neurology, 2018
Background. In the past, studies on the lateralization of the left and right hemispheres of the brain suggested that depression is dominated by the right hemisphere of the brain, but the neural basis of this theory remains unclear. Method.
Mi Li, Hongpei Xu, Shengfu Lu
doaj   +1 more source

Subacute aphasia recovery is associated with resting‐state connectivity within and beyond the language network

Annals of Clinical and Translational Neurology, 2023
Objective To examine changes to connectivity after aphasia treatment in the first 3 months after stroke. Methods Twenty people experiencing aphasia within the first 3 months of stroke completed MRI before and immediately following 15 hours of language ...
Melissa D. Stockbridge, Andreia V. Faria, Julius Fridriksson, Chris Rorden, Leonardo Bonilha, Argye E. Hillis   +5 more
doaj   +1 more source