Results 41 to 50 of about 39,905 (162)

On A Class of Degenerate And Singular Monge-Ampère Equations [PDF]

open access: yesarXiv, 2019
In this paper we shall prove the existence, uniqueness and global H$\ddot{o}$lder continuity for the Dirichlet problem of a class of Monge-Amp\`ere type equations which may be degenerate and singular on the boundary of convex domains. We will establish a relation of the H$\ddot{o}$lder exponent for the solutions with the convexity for the domains.
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Continuous Wavelets on Compact Manifolds [PDF]

open access: yes, 2008
Let $\bf M$ be a smooth compact oriented Riemannian manifold, and let $\Delta_{\bf M}$ be the Laplace-Beltrami operator on ${\bf M}$. Say $0 \neq f \in \mathcal{S}(\RR^+)$, and that $f(0) = 0$. For $t > 0$, let $K_t(x,y)$ denote the kernel of $f(t^2 \Delta_{\bf M})$. We show that $K_t$ is well-localized near the diagonal, in the sense that it satisfies
arxiv   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Tracial gauge norms on finite von Neumann algebras satisfying the weak Dixmier property [PDF]

open access: yesarXiv, 2007
In this paper we set up a representation theorem for tracial gauge norms on finite von Neumann algebras satisfying the weak Dixmier property in terms of Ky Fan norms. Examples of tracial gauge norms on finite von Neumann algebras satisfying the weak Dixmier property include unitarily invariant norms on finite factors (type ${\rm II}\sb 1$ factors and ...
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Besov spaces of self-affine lattice tilings and pointwise regularity [PDF]

open access: yesarXiv, 2015
We investigate Besov spaces of self-affine tilings of ${\Bbb R}^{n}$ and discuss various characterizations of those Besov spaces. We see what is a finite set of functions which generates the Besov spaces from a view of multiresolution approximation on self-affine lattice tilings of ${\Bbb R}^{n}$.
arxiv  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

H$\ddot{o}$lder continuity for stochastic fractional heat equation with colored noise [PDF]

open access: yesarXiv, 2016
In this paper, we consider semilinear stochastic fractional heat equation $\frac{\partial}{\partial t}u_{\beta,t}(x)=\triangle^{\alpha/2}u_{\beta,t}(x)+\sigma(u_{\beta,t}(x))\eta_{\beta}$. The Gaussian noise $\eta_{\beta}$ is assumed to be colored in space with covariance of the form $E(\eta_{\beta}(t,x)\eta_{\beta}(s,y))=\delta(t-s)f_{\beta}(x-y ...
arxiv  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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