Results 51 to 60 of about 39,905 (162)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

On Fourier multipliers in function spaces with partial Hölder condition and their application to the linearized Cahn-Hilliard equation with dynamic boundary conditions [PDF]

arXiv, 2014
We give relatively simple sufficient conditions on a Fourier multiplier, so that it maps functions with the H$\ddot{o}$lder property with respect to a part of the variables to functions with the H$o$lder property with respect to all variables. With the using of these sufficient conditions we prove the solvability in H$\ddot{o}$lder classes of the ...
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Hölder continuity of the integrated density of states for Extended Harper's Model with Liouville frequency [PDF]

arXiv, 2017
In this paper, we study the non-self-dual extended Harper's model with a Liouville frequency. Based on the work of \cite{SY}, we show that the integrated density of states (IDS for short) of the model is $\frac{1}{2}$-H$\ddot{\text{o}}$lder continuous. As an application, we also obtain the Carleson homogeneity of the spectrum.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Higher-order Derivative Local Time for Fractional Ornstein-Uhlenbeck Processes [PDF]

arXiv, 2018
In this article, existence of the $k$-th order derivatives of local time $ \widehat{\alpha}^{(k)}(x,t)$ is considered for two d-dimensional fractional Ornstein-Uhlenbeck processes $X^{H_1}_t$ and $\widetilde{X}^{H_2}_s$ with Hurst parameters $H_1$ and $H_2$, respectively.
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Operator inequalities associated with Hölder–McCarthy and Kantorovich inequalities

Journal of Inequalities and Applications, 1998
We discuss operator inequalities associated with Hölder–McCarthy and Kantorovich inequalities. We give a complementary inequality of Hölder–McCarthy one as an extension of [2] and also we give an application to the order preserving power inequality.
openaire   +1 more source

Regularity and geometric character of solution of a degenerate parabolic equation [PDF]

arXiv, 2015
This work studies the regularity and the geometric significance of solution of the Cauchy problem for a degenerate parabolic equation $u_{t}=\Delta{}u^{m}$. Our main objective is to improve the H$\ddot{o}$lder estimate obtained by pioneers and then, to show the geometric characteristic of free boundary of degenerate parabolic equation. To be exact, the
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source