Results 31 to 40 of about 257,472 (224)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Czy prawu potrzebny jest heros? Reinterpretacja sędziego – Herkulesa w świetle myśli starożytnej

open access: yesActa Iuris Stetinensis, 2022
In his work “Law’s Empire”, Ronald Dworkin made the famous comparison that the judge should be like the mythical Hercules. In the modern interpretation, we most often follow the path mapped out by Rawls and Habermas, understanding the judge-Hercules as ...
Anna Ceglarska
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Contribución al Conocimiento de las Aguas Termo Minerales de Puente del Inca

open access: yes, 1924
Fil: Corti, Hércules. Ministerio de Agricultura.
Corti, Hércules
core   +1 more source

Escultura griega, Hércules arquero

open access: yes, 2009
Vidrio, Negativo, 95 x 118mm, Gelatino Bromuro, S_integro, E_IntegraImagen tomada de un libro con escultura griega, Hércules arqueroUnidad ...

core   +1 more source

Poetisk invention eller politisk intention?

open access: yesTidskrift för Litteraturvetenskap, 2015
Poetic Invention or Political Intention: Magnus Rönnow’s poem, Hercules Genuinus Carolus Duodecimus Magnae Scandinaviae Imperator (1706/7?) as causa belli.
Elena Dahlberg
doaj   +1 more source

Hércules en el iardín criminológico [PDF]

open access: yes, 2016
Hércules en el iardín ...
De la Barreda Solórzano, Luis
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Estrategia de marketing digital para la creación de la marca personal “Hércules” marketing digital para escritores.

open access: yes, 2022
La creación de una marca personal tiene diferentes fases, desde comprender teóricamente el mundo del internet de las cosas, las técnicas de redacción para páginas web, medios digitales el manejo de las redes sociales y el marketing digital.
Hércules Ramírez, César Isaac
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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