Results 31 to 40 of about 157,606 (247)
Cell line derived xenograft mouse models are a suitable in vivo model for studying tumor budding in colorectal cancer [PDF]
, 2019 Tumor budding (TB) is an important prognostic parameter in colorectal cancer (CRC) and associated with metastasis. However, the mechanisms of TB have not been fully elucidated and a major limitation is the absence of in vivo models.Dawson, Heather, De Wever, Olivier, Demetter, Pieter, Galván, José A., Georges, Laurent M. C., Lugli, Alessandro, Zlobec, Inti +6 morecore +2 more sourcesPerceptions des personnels médicaux et para-médicaux sur la gestion des déchets biomédicaux
Revue Congolaise des Sciences et TechnologiesLa gestion des déchets médicaux est une préoccupation mondiale de Santé Publique. Notre étude a consisté à déterminer les perceptions des acteurs médicaux et paramédicaux sur la gestion des déchets biomédicaux. Pour collecter les données dont nous avions Jean Claude Liyandja Impofi, Jeannette Luboya Muisangie, Gaby Kamulumba Kayembe, Denis Lopema Ongala, Stanislas Alain Mbuyi Mpoyi, Astrid Luwolo Tolompobo, Don de Dieu Mulunda Bigabwa, Papy Bosandu Aluka, Pacifique Irenge Lya Hamisi, Alexis Nienie Bwabitulu +9 moredoaj +1 more sourceNIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]
, 2012 Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.Allili, Nassira, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Herve, Dominique, Jouvent, Eric, Yao, Ming +6 morecore +1 more sourceBivalirudin started during emergency transport for primary PCI. [PDF]
, 2013 BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).Berg, J. van den, Bernstein, D., Clayton, T., Clemmensen, P., Coste, P., Deliargyris, E.N., Eggink, G.J., et al., Goldstein, P., Grunsven, P. van, Hamm, C.W., Hamon, M., Hof, A. van't, Huber, K., Lapostolle, F., Nef, H., Nibbe, L., Orto, M. Campo dell', Pocock, S., Prats, J., Schuette, D., Soulat, L., Steg, P.G., Steinmetz, J., Verheugt, F.W.A., Zeymer, U. +25 morecore +1 more sourceCirculating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study [PDF]
, 2018 Background: Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor ...Abroug, S., Alcourt, Y., Allam, H., Antonelli, M., Aubrey, A., Bachoumas, K., Bangert, K., Barthelemy, R., Bartoli, C., Baudrillart, L., Bayer, S., Beeken, T., Beeker, T., Begot, E., Beishuizen, A., Beishuizen, B., Berghe, C., Bergmann, A., Berquier, G., Besancenot, H., Blet, A., Bloos, F., Bloos, P., Bodet-Contentin, L., Boivin, A., Bongiovanni, C., Bonnet, F., Border, N., Bos-Burgmeijer, M., Bouadma, L., Bouhours, G., Bourdier, J., Bourzeix, P., Braad, A., Brick, L., Brulls, C., Buelens, I., Calvat, S., Caumon, E., Cayot, S., Chapellas, C., Chassier, C., Chenaf, S., Chousterman, B. G., Clere-Jehl, R., Colin, G., Collienne, C., Constantin, J. -M., Conte, M., Cornet, A., Cracco, C., Cupaciu, A., Cutuli, S. L., D'Arrigo, S., Daix, T., Damoisel, C., De Heer, G., De Schryver, N., Deiler, V., Deisz, R., Delabranche, X., Delmas, J., Denou, F., Dequin, P. F., Desachy, A., Deschamps, A., Deye, N., Dhif, N., Di Somma, S., Digravio, V., Dubief, E., Duchambon, A. -A., Dugernier, T., Dujardin, M. -F., Ehrmann, S., Fally, M. A., Fedou, A. -L., Feld, F., Feliot, E., Fesard, P., Fiancette, M., Fournier, M. -C., Francois, B., Freys, G., Frings, D., Fuhrmann, V., Fullekrug, B., Gaillard, T., Galy, A., Garcon, P., Garot, D., Gaudry, S., Gaugain, S., Gayat, E., Geukens, P., Geven, C., Godet, T., Gonnert, F., Gouhier, C., Goury, A., Guerin, R., Guillon, A., Guyon, M., Hartmann, O., Haucke, A., Hecketsweiler, S., Heenen, S., Hemelaar, P., Henin, P., Henker, R., Henry-Lagarrigue, M., Herafa, I., Heunks, L., Hoedemaekers, A., Hohn, A., Hollinger, A., Huberlant, V., Huot, B., Jabaudon, M., Jacob, L., Janisch, T., Jaschinski, U., Joret, A., Jouan, Y., Kehl, L., Kelly, D. S., Kerdjana, L., Kerinn, M., Kerymel, M., Kluge, S., Kohlberg, K. K., Kolanos, S., Kortgen, A., Kreuser, I., Kummerlen, C., La Combe, B., La Foucher, B., Lacherade, J. -C., Lafon, C., Laissi, M., Laleu, S., Lascarrou, J. -B., Lascarrou, J. B., Lasocki, S., Laterre, P. -F., Laterre, P. F., Launoy, A., Laurent, Y., Lebert, C., Leblanc, D., Lebreton, S., Legall, C., Legrand, M., Legras, A., Lematte, M., Leone, F. E., Lessinger, J. -M., Letrou, S., Lindau, S., Loiez, A., Louadah, B., Lucht, A., Ludes, P. O., Mabilat, C., Magalhaes, E., Mairesse, J., Malissin, I., Mancia, C., Manivet, P., Maquigneau, N., Martin-Levevre, L., Marx, G., Marx, N., Massat, S., Mebazaa, A., Megarbane, B., Meier, B., Meier-Hellmann, A., Meinig, T., Mercier, E., Messika, J., Metzger, C., Meybohm, P., Meyer, A., Meziani, F., Mourvillier, B., Muller, J., Mutlak, H., Navarin, S., Neuville, M., Nierhaus, A., Nouaille, M., Orru, M., Oueslati, H., Papendorp, S., Pascal, J., Perbet, S., Petre, H., Pezechk, J., Pichon, N., Pickkers, P., Pierre, V., Pottecher, J., Quatrocchi, D., Quattrochi, D., Rabouel, Y., Radji, S., Radjou, A., Rahmani, H., Reignier, J., Renard, S., Ricard, J. -D., Ringeis, G., Rinket, M., Robert, A., Robin, L., Rodier, N., Rolhion, C., Rommer, M., Roovers, N., Roszyk, L., Rouleau, S., Rousseau, C., Rouve, E., Roux, D., Ruimy, A., Russo, V., Salmon, C., Schedler, D., Schindler, A., Schnell, D., Schreiber, J., Schroder, D., Schuerholz, T., Schwope, K., Scigalla, P., Sebastien, L., Sensen, B., Siedler, S., Siewecke, A., Simeon-Vieules, V., Simon, T. -P., Simona, S., Singer, B., Soffker, G., Sonneville, R., Soyer, B., Struck, J., Szozot, M., Thibault, S., Thirifays, A., Thomas-Ruddel, D., Timsit, J. -F., Trine, H., Trof, R. J., Vallecoccia, M. S., Van Der Hoeven, H., Van Wezel, H., Varchetta, A., Verlhac, C., Vermeijden, J., Victori, G., Vignon, P., Vinatier, I., Vinetti, M., Voicu, S., Wetsch, W., Wichmann, D., Wittebole, X., Yehia, A., Zacharowski, K. D., Zanquila, M., Zapatero, D. C., Zinzonni, V. E., Zoccoli, G. +274 morecore +1 more sourceDifferential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study
Arthritis Care &Research, EarlyView.Objective
Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.Sophie Hu, Marie‐Eve Carrier, Marie‐Claude Geoffroy, Meira Golberg, Linda Kwakkenbos, Susan J. Bartlett, Catherine Fortuné, Amy Gietzen, Karen Gottesman, Geneviève Guillot, Laura K. Hummers, Amanda Lawrie‐Jones, Vanessa L. Malcarne, Michelle Richard, Maureen Sauvé, Luc Mouthon, Andrea Benedetti, Brett D. Thombs, on behalf of the SPIN Investigators, Claire E. Adams, Marie Hudson, Maureen D. Mayes, James Stempel, Robyn K. Wojeck, Christian Agard, Laurent Alric, Marc André, Floryan Beaslay, Elana J. Bernstein, Sabine Berthier, Lyne Bissonnette, Sophie Blaise, Eva Bories, Alessandra Bruns, Carlotta Cacciatore, Patricia Carreira, Marion Casadevall, Benjamin Chaigne, Lorinda Chung, Benjamin Crichi, Thylbert Deltombe, Christopher P. Denton, Tannvir Desroche, Robyn Domsic, James V. Dunne, Bertrand Dunogue, Regina Fare, Dominique Farge‐Bancel, Paul R. Fortin, Tracy Frech, Loraine Gauzère, Anne Gerber, Jessica K. Gordon, Brigitte Granel‐Rey, Aurélien Guffroy, Geneviève Gyger, Eric Hachulla, Daphna Harel, Monique Hinchcliff, Sabrina Hoa, Michael Hugues, Alena Ikic, Sindhu R. Johnson, Nader Khalidi, Kimberly S. Lakin, Marc Lambert, Maggie Larche, David Launay, Yvonne C. Lee, Paul Legendre, Catarina Leite, Hélène Maillard, Nancy Maltez, Joanne Manning, Isabelle Marie, Maria Martin Lopez, Thierry Martin, Ariel Masetto, Arsène Mekinian, Sheila Melchor Díaz, Morgane Mourguet, Christelle Nguyen, Karen Nielsen, Mandana Nikpour, Louis Olagne, Vincent Poindron, Janet Pope, Susanna Proudman, Grégory Pugnet, Loïc Raffray, François Rannou, Alexis Régent, Frederic Renou, Sébastien Rivière, David Robinson, Esther Rodríguez Almazar, Tatiana Sofia Rodríguez‐Reyna, Sophie Roux, Perrine Smets, Vincent Sobanski, Robert F. Spiera, Virginia Steen, Evelyn Sutton, Carter Thorne, Damien Vagner, John Varga, Pearce Wilcox, Vanessa Cook, Cassidy Dal Santo, Monica D'Onofrio, Elsa‐Lynn Nassar +110 morewiley +1 more sourceIntensive Chemotherapy With or Without Midostaurin in Adults ≥ 60 Years Old With FLT3‐Mutated AML: A FILO‐DATAML‐PETHEMA Real‐World Study
American Journal of Hematology, EarlyView.ABSTRACT
The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...Gaspar Aspas Requena, Pau Montesinos, Emilie Bérard, Sarah Bertoli, Rebeca Rodríguez‐Veiga, Celestine Simand, Laura Torres, Pierre Peterlin, Mar Tormo, Rudy Birsen, Juan Miguel Bergua‐Burgues, Emmanuelle Tavernier, Teresa Bernal del Castillo, Martin Carré, Cristina Gil, Adrien Contejean, Eduardo Rodríguez‐Arbolí, Corentin Orvain, Carlos Rodríguez‐Medina, Lauren Veronese, Maria Jose Sayas Lloris, Eric Delabesse, Josefina Serrano, Ariane Mineur, María García‐Fortes, Romain Guieze, Maria Luz Amigo, Arnaud Pigneux, Lorenzo Algarra Algarra, Christian Recher, Pierre‐Yves Dumas, David Martínez‐Cuadrón +31 morewiley +1 more sourceSanta Caterina degli ospedali
Italies, 2023 Caterina Fieschi (1447-1510) était une aristocrate de Gênes, souhaitant s’engager dans la vie religieuse mais forcée au mariage par sa famille. Après avoir eu une vision mystique, elle consacra toute son existence aux miséreux et aux malades, impliquant ...Valeria Puccinidoaj Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification
American Journal of Hematology, EarlyView.ABSTRACT
Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...Sara El Aouhel, Vanessa Bellegarde, Stennio Da Silva Faria, Tristan St‐Laurent, Estelle Lecluze, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Frédéric Galactéros, Pablo Bartolucci, Marc‐André Legault, Guillaume Lettre, Thomas Pincez +10 morewiley +1 more source