Results 221 to 230 of about 420,413 (259)

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Optimizing NiMo Electrocatalyst Coatings for Hydrogen Evolution in Alkaline Electrolysis With The Machine Learning‐Guided Autonomous Platform CatBot

Advanced Functional Materials, EarlyView.
This work presents a closed‐loop optimization workflow integrating CatBot, an automated synthesis and testing system, to discover NiMo hydrogen‐evolution catalysts. CatBot synthesised and evaluated 228 unique samples, identifying the best performing catalysts for transfer to nickel‐foam electrodes. The best candidate is highly active, reaching 1 Acm−2${
Paolo Vincenzo Freiesleben de Blasio, Jonas Elsborg, Elif Coşkun, Andreas Burger, Pradipkumar Manubhai Leuaa, Thu Pham Anh Phan, Jin Hyun Chang, Christodoulos Chatzichristodoulou   +7 more
wiley   +1 more source

Unstable Vortices, Sharp Non-Uniqueness with Forcing, and Global Smooth Solutions for the SQG Equation. [PDF]

Arch Ration Mech Anal
Castro Á, Faraco D, Mengual F, Solera M.   +3 more
europepmc   +1 more source

Penalization method to convert Bayesian optimization methods into batch multi-objective Bayesian optimization methods. [PDF]

PLoS One
Holder A, DeBruin H, Sestito JM.
europepmc   +1 more source

Influence of 3D Printing Parameters on Apparent Resistivity, Repeatability and Time-Dependent Drift of Conductive PLA. [PDF]

Polymers (Basel)
Popescu D, Popescu D, Cula Ș, Parpală LF.   +3 more
europepmc   +1 more source

Spectral methods for Neural Integral Equations. [PDF]

Ric Mat
Zappala E.
europepmc   +1 more source

Quantitative assessment of gastrointestinal motility in neonatal rats by real-time 3D photoacoustic imaging: A feasibility study. [PDF]

Photoacoustics
Huang T, Li L, Sun Y, Wang Y, Hou X, Li C.   +5 more
europepmc   +1 more source