Results 71 to 80 of about 11,920,025 (242)

Towards a Digital Twin of Heritage Buildings: Scan-to-BIM Documentation and DEMATEL-Based Analysis of LiDAR, IoT and AI Integration Pathways

Applied Sciences
This study proposes an integrated approach to the digital documentation and system-level analysis of heritage buildings, combining LiDAR-based data acquisition, H-BIM modelling and DEMATEL analysis.
Grzegorz Oleniacz, Izabela Skrzypczak, Agnieszka Leśniak, Maria Mrówczyńska, Piotr Ochab, Joanna Figurska-Dudek   +5 more
doaj   +1 more source

Fc‐Dependent Targeting of the GAS6–MERTK Axis With Monoclonal and Bispecific Antibodies Overcomes Drug Resistance Across EGFR Mutations in Exons 19, 20, and 21

Advanced Science, EarlyView.
EGFR mutations drive a substantial fraction of non‐small cell lung cancers (NSCLC) and are effectively targeted by tyrosine kinase inhibitors (TKIs), including osimertinib. However, resistance inevitably develops through secondary mutations and compensatory receptor activation, including the GAS6 receptor MERTK.
Suvendu Giri, Boobash Raj Selvadurai, Nitin Gupta, Arturo Simoni‐Nieves, Alessandro Genna, Moshit Lindzen, Rishita Chatterjee, Marieke Van Daele, Deepthi Ramesh Kumar, Mirie Zerbib, Roni Oren, Isabelle Sophie Meijer, Elisabeth Franziska Wippich, Yahel Avraham, Rony Dahan, Yuya Haga, Laura E. Kilpatrick, Simon Platt, Stephen J. Hill, Lipika R. Pal, Eytan Ruppin, Yasuo Tsutsumi, Eliane Hadas Yardeni, Muhammad Abu Ahmad, Olga Radinsky, Donatella Romaniello, Mattia Lauriola, Angel Porgador, Yosef Yarden   +28 more
wiley   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

Advanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola, Keun‐Young Kim, Ziyao Shen, Guy A. Perkins, Muna Poudel, Yoonjin Lim, Hyejeong Choi, Soo‐Ho Choi, Mark H. Ellisman, Robert N. Weinreb, Won‐Kyu Ju   +10 more
wiley   +1 more source

H-bim na gestão da segurança elétrica:

Encontro Latino-americano e Europeu sobre Edificações e Comunidades Sustentáveis (euroELECS)
A necessidade de gerir espaços de forma sustentável se demonstra um desafio quando se trata de uma edificação patrimonial. Este artigo investiga a aplicação do Heritage Building Information Modeling (H-BIM) como ferramenta estratégica para a operação de sistemas elétricos.
Pedro Henrique Torres de Carvalho, Cainã Bittencourt Dutton Felix da Silva, Assed Naked Haddad   +2 more
openaire   +1 more source

An investigation into the mechanisms by which bim gene expression is regulated in sympathetic neurons [PDF]

, 2010
Neuronal apoptosis plays a critical role in development and disease. Developing sympathetic neurons require nerve growth factor (NGF) for their survival and die by apoptosis in its absence.
Hughes, R.
core  

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source

An automated nD model creation on BIM models

Organization, Technology and Management in Construction: An International Journal, 2020
The construction technology (CONTEC) method was originally developed for automated CONTEC planning and project management based on the data in the form of a budget or bill of quantities.
Vycital Miroslav, Jarský Cenek
doaj   +1 more source

From laser scanning to H-Bim: A case study

, 2020
[ES] Queriendo dar respuesta a las preguntas que el anterior estudio precedente efectuado con una estación total (Trimble S6 Vision) no pudo concretar, el artículo comenta los resultados obtenidos con las adquisiciones de digitalización láser 3D y las bases de datos fotográficas. La precisión, garantizada por la tecnología de medida, ha permitido medir
Rossi, A., Palmero Iglesias, Luis Manuel, Palmieri, U.   +2 more
openaire   +2 more sources

Análise da Implementação e do Impacto do BIM no Brasil [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.Avaliação da situação da metodologia BIM (Building Information Modeling - Modelagem da Informação da Construção) no mundo, e a perspectiva deste o mercado ...
Cardoso Masotti, Luís Felipe
core  

How to Navigate Disrupted Business Models in the 21st Century: At the Crossroads of the Circular Economy and the Industry 4.0 Transition

Business Strategy and the Environment, EarlyView.
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter, Rui Torres de Oliveira, Shane Mathews, Leonie Barner   +3 more
wiley   +1 more source